Dr John Sleep
Research Fellow
Randall Division of Cell and Molecular Biophysics
Telephone: +44 (0)20 7848 6473
Fax: +44 (0)20 7848 6435
Email: john.sleep@kcl.ac.uk
Biography
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B.A. Physics Cambridge 1972
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Ph.D. Biophysics, London 1975
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Muscular Dystrophy Research Fellowship UCLA 1976 - 1978
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Research Assistant University College 1979 - 1980
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Scientific Staff, MRC Unit of Muscle and Cell Motility 1980 - 2000
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MRC External Scientific Staff 2000 -
Research Interests
Actomyosin crossbridge cycle. Elastic properties of red blood cell
Selected publications
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Lewalle, A, Steffen,W., Stevenson, O., Zhenqian, O. and Sleep, J, (2008) Single-Molecule Measurement of the Stiffness of the Rigor Myosin Head Biophysical Journal 94, 2160 - 2169
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Evans, J., Gratzer, W., Mohandas, N., Parker, P. & Sleep, J. (2008) Fluctuations of the Red Blood Cell Membrane: Relation to Mechanical Properties and Lack of ATP Dependence Biophysical Journal 94, 4134–4144
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Sleep, J, Lewalle, A, and Smith, D. (2006) Reconciling the working strokes of a single head of skeletal muscle myosin estimated from laser-trap experiments and crystal structures Proc. Natl. Acad. Sci. 103, 1278-1282