Published papers
As various journals are no longer able to host supplemental data for publications on their own websites, we are now making this data available on our website. Please find below the supplemental data for individual papers published by our division.
Manuscript in review
Madeleine J. Oudin, Martina Sonego, Carl Hobbs, Gareth Williams, Giovanna Lalli and Patrick Doherty. Real time imaging reveals an essential role for the FGF receptor and endocannabinoid signaling in polarising neuroblast migration in the RMS
Video 1: Neuroblasts migrating in the RMS
Brain slices containing RMS neuroblasts (green) labelled with GFP by in vivo electroporation were imaged every 3 min for 3 h using a spinning disk confocal microscope (Perkin Elmer). (12 frames/sec)
Video 2: Migration of RMS neuroblasts treated with CB1/2 antagonists
Brain slices containing RMS neuroblasts (green) labelled with GFP by in vivo electroporation were treated with 1 µM AM251 + JTE-907 (CB1/2 antagonists) and imaged every 3 min for 3 h using a spinning disk confocal microscope. (12 frames/sec)
Video 3: Migration of RMS neuroblasts treated with CB1/2 agonists
Brain slices containing RMS neuroblasts (green) labelled with GFP by in vivo electroporation were treated with 1 µM ACEA+JWH-133 (CB1/2 agonists) and imaged every 3 min for 3 h using a spinning disk confocal microscope. (12 frames/sec)
Video 4: Migration of RMS neuroblasts treated with FGFR inhibitor
Brain slices containing RMS neuroblasts (green) labelled with GFP by in vivo electroporation were treated with 1 µM PD173034 (FGFR inhibitor) and imaged every 3 min for 3 h using a spinning disk confocal microscope. (12 frames/sec)
Video 5: Migration of RMS neuroblasts treated with FGF-2
Brain slices containing RMS neuroblasts (green) labelled with GFP by in vivo electroporation were treated with 50 ng/ml FGF-2 and imaged every 3 min for 3 h using a spinning disk confocal microscope. (12 frames/sec)
Oudin MJ, Gajendra S, Williams G, Hobbs C, Lalli G & Doherty P (2010). Endocannabinoids regulate the migration of SVZ-derived neuroblasts in the post natal brain. Journal of Neuroscience, accepted for publication
Supplementary data