Differentiation of pluripotent stem cells to bone and cartilage cell lineages
1st Supervisor: Professor Agi Grigoriadis
2nd Supervisor: Professor Paul Sharpe
Description of project
This project utilizes murine and human pluripotent stem cells such as Embryonic Stem (ES) and induced Pluripotent Stem (iPS) cells to understand the molecular mechanisms that control the specification of these cells and further expansion and commitment of specific precursors to the osteoblast, chondrocyte and osteoclast lineages. These studies are important for understanding the embryonic development of bone and cartilage tissues as well as for generating useful cell populations for therapeutic purposes.
Duration of project: 4 years
Contact for further information
Professor Agi Grigoriadis
Research Topic: Craniofacial Development and Stem Cell Biology
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