The future

Genetics: growing teeth in the laboratory

The discovery of the molecular basis of the human genetic code, first uncovered during the 1950s in large measure by King's scientists is now being applied to understanding the embryonic development of teeth. One major aspect of the work of the Institute is in seeking to discover the mechanism by which the genetic code is expressed in the embryo and so pave the way for the regeneration of damaged teeth in adults.

The research team is led by Professor Paul Sharpe of the Cell and Developmental Biology research group and will benefit from the planned opening of the Centre for Regenerative Dentistry.

Another exciting development has been the formation in 2002 of a start-up company, Odontis Ltd, which aims eventually to grow replacement human teeth using stem cell technology to overcome rejection problems.

The study of protein growth factors is one further example of the Institute's research, with the objective of understanding human facial abnormalities and disease.