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MitoDNA ®

MitoDNA® Service Lab

Mitochondria contain their own  extra-chromosomal genome, a small (16.6kb) circular molecule of double stranded DNA (MtDNA) present in hundreds to thousands of copies in each cell. Each mitochondrion contains between 02-10 copies of MtDNA. MtDNA comprises of 37genes (13 of them code for components of OXPHOS, rest tRNA and rRNA) which are essential for cell function and survival. The amount of MtDNA can vary in cells in response to physiological stimuli and during disease.

     MtDNA Fig1

     Mitochondria contain their own DNA. (Figure courtesy of National Human                                                    Genome Research Institute)

The mitoDNA® Service Lab at King’s College London has developed techniques for quantitative measurement of mtDNA content. Our method has been designed and optimised by specialists in the field to overcome common problems associated with Mt DNA quantification (Please see MtDNA assay for more information). The service is better value and less hassle than setting up the assay in-house and you are guaranteed to receive the best service from our team with in depth experience of developing and delivering the methodology.

     MtDNA Fig2

          Mitochondria DNA (mtDNA) content quantification assay description

mitoDNA® is a registered Community Trademark of King’s College London, with number 012279981

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