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Department of Medical & Molecular Genetics

About us

The Department of Medical and Molecular Genetics uses the advances from the Human Genome project, new technologies in genomics and cell biology, and our expertise in statistics, genetic epidemiology and bioinformatics to explore human genetic variation and its relationship to human disease.    

Our research portfolio includes gene discovery in monogenic disorders and extreme disease phenotypes by next generation sequencing, the identification of susceptibility genes for common complex disorders by genome-wide association scans, the study of pathogenesis and therapeutics in neurological disease, the epigenetics of development and disease, genomic and functional studies in cancer, and the development and application of statistical and bioinformatic methods to the study of complex disease.   

The Department has close links with the Guy’s and St Thomas’s Hospitals NHS Trust Clinical Genetics service, and houses the Biomedical Research Centre’s state of the art Genomics Core Facility, which is equipped with next generation sequencers, robotics and array scanners for a variety of high throughput genomics applications. It is also embedded within the King’s Health Partners Academic Health Sciences Centre through the Genetics, Rheumatology, Infection, Immunology and Dermatology Clinical Academic Group.   

Our mission embraces both fundamental scientific discovery and its application to new and improved diagnostics and therapeutics via the Translational Genetics theme in our Biomedical Research Centre.

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