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Professor Stefan Bornstein

Professor Stefan Bornstein

Chair and Honorary Consultant - 

Endocrinology and Diabetes

Division of Diabetes & Nutritional Sciences

Contact details:
Rayne Institute, Denmark Hill Campus,
London, SE5 9NU.
E-mail: stefan.bornstein@kcl.ac.uk
Personal Assistant: Gina Cady
Email: gina.cady@kcl.ac.uk
Tel: 020 7848 0159


Biography


Prof. Stefan Bornstein graduated from the University of Ulm and Miami in 1988. He completed his residency in internal medicine in 1994 and specialised in endocrinology and diabetes. He won several awards including the 1st prize for “The new generation of academics” and the Marius-Tausk-Award of the German Endocrine Society. Recipient of the Heisenberg Award of the German Research Foundation (DFG), Bornstein has been working for many years as a research scholar and acting unit chief at the endocrine branch at the National Institutes of Health in Bethesda, United States. From 2001 – 2004 he was Professor and vice-chair of the department of endocrinology and metabolism at the University of Düsseldorf, Germany. 

Since 2004, Bornstein is Director and Chair of the Department of Medicine at the University of Dresden, Germany. In 2012 he became Dean of International Affairs and Development at the University of Dresden. He is Chair and Honorary Consultant, Endocrinology and Diabetes, King’s College London, UK since 2013. 

His main research interests focus on lipid-, steroid- and catecholamine metabolism, immune endocrine crosstalk, type 1 diabetes, islet transplantation and mechanisms of hypertension in the metabolic syndrome. 
He has (co)authored more than 500 Medline-cited scientific papers and contributed to numerous books.

Grants


Professor Bornstein’s departments across Kings College London and Dresden University currently generate up to €10 million per year of grant money. This includes funding from the EU, NIH, €30.000  for the strategic partnership between KCL and Dresden University from DFG (the German Ministry of Health), foundations and industry.


German Centres for Health Research: German Centre for Diabetes Research (DZD) as a partner of the Helmholtz Centre Munich
Sponsor: Federal Ministry of Education and Research
Period of time 1.1.2010 - 31.12.2015
Amount 12.600000 €

Collaborative Research Centre 655 "Cells into tissues: Stem cell and progenitor commitment and interactions during tissue formation"
Sponsor German Research Foundation
Period of time 1.7.2005 - 30.6.2017
Amount 39.200.000 € 

Clinical Research Unit (CRU) 252 "Microenvironment of the adrenal in health and disease
Sponsor German Research Foundation
Period of time 1.7.2011 - 30.6.2014
Amount 3.049.100 €

Collaborative Research Centre / Transregio 127 "biology of xenogeneic cell, tissue and organ transplantation – from bench to bedside"
Sponsor German Research Foundation
Period of time 1.7.2012 - 30.6.2016
Amount 13.513.000 € 

Establishment of the German Australian Institute for Translational Medicine (GAITM)
Sponsor: Federal Ministry of Education and Research 
Period of time: 1.7.2010 - 31.12.2014
Amount: 333.600 €

Imaging and Curing Environmental Metabolic Diseases - ICEMED,Topic 2: System biology
Sponsor: Federal Ministry of Education and Research
Period of time: 1.4.2012 - 31.3.2017
Amount: 210.000 €

Cell therapy for the treatment of Congenital adrenal hyperplasia (CAH) using an implantable medical device
Sponsor: International Fund raising for research on Congenital Adrenal Hyperplasia
Period of time: 1.11.2013 - 31.10.2014
Amount: 76.500 €



NHMRC: 

Title: Long-term metabolic effects of stress
and antidepressants: a novel translational animal paradigm of drug induced obesity
Period of time: 2014 - 2016
Amount: 501.174 AUD

Title:  Mechanism of protection of islet beta cells from T1D by heparin sulfate
Period of time: 2013 - 2015
Amount: 581.408 AUD



Publications


1. Lipidomic profiling before and after Roux-en-Y gastric bypass in obese patients with diabetes. Graessler, J.,…. Bornstein, S. R et al.  In: PHARMACOGENOMICS J. Jun 2014.

Contribution to journal › Article

2. Oncologic Resection Achieving R0 Margins Improves Disease-Free Survival in Parathyroid Cancer. Schulte, K. M.,… Bornstein, S. R. et al. In: Ann Surg Oncol. Jun 2014.

Contribution to journal › Article

3. Blocking CD40-TRAF6 signalling is a therapeutic target in obesity-associated insulin resistance. Noelle, R., .. Bornstein, S. R. et al. In: Proc Natl Acad Sci USA, Feb 2014.

Contribution to journal › Article

4. Transplantation of pancreatic islets to adrenal gland is promoted by agonists of growth-hormone-releasing hormone. Schubert, U., … Bornstein, S. R. et al. In : Proc Natl Acad Sci USA, Feb 2013.

5. Predisposing factors for adrenal insufficiency. Bornstein, S. R. In: N Engl J Med.  May 2009.

6. Adrenomedullary dysplasia and hypofunction in patients with classic 21-hydroxylase deficiency. Merke DP., .… Bornstein SR et al. N Engl J Med. Nov 2000.

7. Transplantation of human islets without immunosuppression. Ludwig B.,… Bornstein SR et al. In: Proc Natl Acad Sci USA, Nov 2013.


Links


PubMed - All Publications

Wikipedia Entry - Stefan Bornstein

About Kings College London

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