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Diabetes Research

Publications

Stephanie Amiel

  1. Hovorka R, Kumareswaran K, Harris J, Allen JM, Elleri D, Xing D, Kollman C, Nodale M, Murphy HR, Dunger DB, Amiel SA, Heller SR, Wilinska ME, Evans ML. Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies. BMJ. 2011 Apr 13;342:d1855
  2. Dunn JT, Anthony K, Amiel SA, Marsden PK. Correction for the effect of rising plasma glucose levels on quantification of MR(glc) with FDG-PET. J Cereb Blood Flow Metab. 2009 May;29(5):1059-67.
  3. Yong PF, Malik R, Arif S, Peakman M, Amiel S, Ibrahim MA, Gough A. Rituximab and omalizumab in severe, refractory insulin allergy. N Engl J Med. 2009 Mar 5;360(10):1045-7.
  4. Rogers H, Turner E, Thompson G, Hopkins D, Amiel SA. Hub-and-spoke model for a 5-day structured patient education programme for people with Type 1 diabetes. Diabet Med. 2009 Sep;26(9):915-20

Paul Banga

  1. Banga JP, Nielsen CH, Gilbert JA, El Fassi D, Hegedus L (2008) Application of new therapies in Graves’ disease and thyroid associated ophthalmopathy: animal models and translation to human clinical trials. Thyroid 18: 973-981.
  2. Padoa CJ, Larsen SL, Hampe CS, Gilbert JA, Dagdan E, Hegedus L, Dunn- Walters D, Banga JP (2009). Clonal relationships between TSH-receptor stimulating antibodies illustrate the effect of hypermutation on antibody function. Immunology 129: 300-308.
  3. Jauregui-Osoro M, Sunasseee K, Weeks AJ, Berry DJ, Paul RL, Cleij M, Banga JP, O’Doherty MJ, Marsden PK, Clarke SEM, Ballinger JR, Szander I, Cheng SY, Blower PJ (2010). Synthesis and biological evaluation of [18F]-tetrafluoroborate: a PET imaging agent for thyroid disease and reporter gene imaging of the sodium-iodide symporter. Eur J Nucl Med Mol Imaging 37: 2108-2116

Pratik Choudhary

  1. Teh MM, Dunn JT, Choudhary P, Samarasinghe Y, Macdonald I, O'Doherty M, Marsden P, Reed LJ, Amiel SA Evolution and resolution of human brain perfusion responses to the stress of induced hypoglycemia. Neuroimage 2010. 53 (Nov): 584-593.
  2. Choudhary P, Lonnen K, Emery CJ, MacDonald IA, MacLeod KM, Amiel SA, Heller SR. Comparing hormonal and symptomatic responses to experimental hypoglycaemia in insulin- and sulphonylurea-treated Type 2 diabetes Diabet Med. 2009;26:665-672
  3. Smith CB, Choudhary P, Pernet A, Hopkins D, Amiel SA. Hypoglycaemia unawareness is associated with reduced adherence to therapeutic decisions in patients with Type 1 diabetes: evidence from a clinical audit. Diabetes Care, 2009 Jul;32(7):1196-8.

Michael Christie

  1. Oak S, Gilliam LK, Landin-Olsson M, Törn C, Kockum I, Pennington CR, Rowley MJ, Christie MR, Banga JP, Hampe CS (2008) Lack of anti-idiotypic antibodies, not presence of the corresponding autoantibodies to glutamate decarboxylase, defines type 1 diabetes. Proc Natl Acad Sci 105: 5471-5476
  2. Weenink SM, Lo J, Stephenson CR, McKinney PA, Ananieva-Jordanova R, Rees Smith B, Furmaniak , Tremble JM, Bodansky HJ, Christie MR (2009) Autoantibodies and associated T-cell responses to determinants within the 831-860 region of the autoantigen IA-2 in Type 1 diabetes. J Autoimmun 33: 147-154
  3. Foot VL, Richardson CC, Jefferson W, Taylor PD, Christie MR (2010) Islets in early life are resistant to detrimental effects of a high-fat maternal diet; a study in rats. Horm Metab Res 44: 923-929

Guo Cai Huang

  1. Zhao M, Amiel SA, Ajami S, Jiang J, Rela M, Heaton N, Huang GC. Amelioration of streptozotocin-induced diabetes in mice with cells derived from human marrow stromal cells. PLoS ONE. 2008 Jul 16;3(7):e2666
  2. Zhao M, Amiel SA, Christie MR, Muiesan P, Srinivasan P, Littlejohn W, Rela M, Arno M, Heaton N, Huang GC. Evidence for the presence of stem cell-like progenitor cells in human adult pancreas. Endocrinol. 2007 Dec;195(3):407-14.
  3. Ramracheya RD, Muller DS, Squires PE, Brereton H, Sugden D, Huang GC, Amiel SA, Jones PM, Persaud SJ. Function and expression of melatonin receptors on human pancreatic islets. J Pineal res 2008; 273-9

Khalida Ismail

  1. Patel A, Maissi E, Chang HC, Rodrigues I, Smith M, Thomas S, Chalder T, Schmidt U, Treasure J, Ismail K. Motivational enhancement therapy with and without cognitive behaviour therapy for Type 1 diabetes: economic evaluation from a randomized controlled trial.Diabet Med. 2011 Apr;28(4):470-9
  2. Nouwen A, Winkley K, Twisk J, Lloyd CE, Peyrot M, Ismail K, Pouwer F; European Depression in Diabetes (EDID) Research Consortium.Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis. Diabetologia. 2010 Dec;53(12):2480-6
  3. Ismail K, Maissi E, Thomas S, Chalder T, Schmidt U, Bartlett J, Patel A, Dickens C, Creed F, Treasure J. A randomised controlled trial of cognitive behaviour therapy and motivational interviewing for people with Type 1 diabetes mellitus with persistent sub-optimal glycaemic control: a Diabetes and Psychological Therapies (ADaPT) study. Health Technol Assess. 2010 May;14(22):1-101, iii-iv

Peter Jones

  1. Hauge-Evans AC, King AJ, Carmignac D, Robinson ICAF, Low MJ, Christie MR, Persaud SJ and Jones PM. (2009) Somatostatin secreted by islet δ-cells fulfils multiple roles as a paracrine regulator of islet function. Diabetes 58 403-411
  2. Bowe JE, Kinsey-Jones JS, O’Byrne KT, King AJ, Persaud SJ and Jones PM (2009) Kisspeptin regulates insulin secretion in vivo and in vitro. Diabetologia 52(5):855-62
  3. Jones PM, Courtney ML, Burns CJ and Persaud SJ (2008) Cell-based treatments for diabetes. Drug Discovery Today 13, 888-893

Aileen King

  1. Islet alpha cell number is maintained in microencapsulated islet transplantation.
    Bohman S, King AJ.
    Biochem Biophys Res Commun. 377(2):729-33, 2008.
  2. Somatostatin secreted by islet δ-cells fulfils multiple roles as a paracrine regulator of islet function.
    AC Hauge-Evans, AJ King, D. Carmignac, ICAF Robinson, MJ Low, MR Christie, S J Persaud and PM Jones.
  3. Co-transplantation of mesenchymal stem cells maintains islet organisation and morphology in mice
    vDiabetologia. 54:1127-35, 2011.

Dany Muller

  1. Muller DS, Liu B, Jones PM and Persaud SJ (2011) Calcium/calmodulin-dependent kinase IV controls glucose-induced Irs2 expression in mouse beta cells via activation of cAMP response element-binding protein. Diabetologia 54 :1109-1120
  2. D Muller, PM Jones and SJ Persaud (2009) Single Cell RT-PCR identification of genes expressed by human islet endocrine cells. Methods in Molecular Biology 560:73-86.
  3. Ramracheya RD, Muller D, Squires PE, Brereton H, Sugden D, Huang GC, Amiel SA, Jones PM and Persaud SJ (2008) Function and expression of melatonin receptors on human pancreatic islets. J. Pineal Res. 44: 273-279

Shanta Persaud

  1. Ramracheya RD, Muller D, Squires PE, Brereton H, Sugden D, Huang GC, Amiel SA, Jones PM and Persaud SJ (2008) Function and expression of melatonin receptors on human pancreatic islets. J. Pineal Res. 44, 273-279
  2. Cantley J, Selman C, Shukla D, Abramov AY, Forstreuter F, Esteban MA, Claret M, Lingard SJ, Clements M, Harten SK, Asare-Anane H, Batterham RL, Herrera P, Persaud SJ, Duchen M, Maxwell PH and Withers DJ (2008) Deletion of the von Hippel-Lindau gene in pancreatic β cells impairs glucose homeostasis in mice. J. Clin. Invest. 119, 125-135
  3. Li C, Jones PM and Persaud SJ (2011) Role of the endocannabinoid system in food intake, energy homeostasis and regulation of the endocrine pancreas. Pharmacology and Therapeutics 129, 307-320

John Pickup

  1. Pickup JC, Sutton AJ. Severe hypoglycaemia and glycaemic control in type 1 diabetes: meta-analysis of multiple daily insulin injections compared with continuous subcutaneous insulin infusion. Diabetic Med 2008; 25: 765-74.
  2. Khan F, Saxl TE, Pickup JC. Fluorescence intensity- and lifetime-based glucose sensing using an engineered high-Kd mutant of glucose/galactose-binding protein. Analyt Biochem 2010; 399: 39-43.
  3. Zhi ZL, Liu B, Jones PM, Pickup JC. Polysaccharide multilayer nanoencapsulation of insulin-producing beta-cells grown as pseudoislets for potential cellular delivery of insulin. Biomacromolecules 2010; 11: 61-616.
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