What's on archive 2011

Biomedical Forum: Methodological Innovation and Personalised Medicine

07 Dec 2011, 13:00-14:00, Lecture Theatre 1, New Hunt's House, Guy's Campus

School / area: Medicine
Department: Biomedical Research Centre
Location: Guy's Campus
Location map: Guy's: detail

"The role of Methodological Innovation en route to Personalised Medicine"

 

Presenters: Professor Anthonius Coolen and Dr Franca Fraternali

 

The aim of personalised medicine is to predict disease progression and response to different treatment protocols at the level of individual patients; this is still not possible to the desired standard of precision and reproducibility.  Predictions are only as good as the data and the mathematical and computational tools used to extract patterns from these data.  While the experimental methods of biomedicine continue to evolve rapidly, the statistical tools used to extract prognostic information from clinical data have hardly changed over the last forty years.  These were in fact developed in an era where computers were few and slow, and never envisaged to handle the quantity and complexity of the medical data that are now available.  Similarly, many biomedical researchers use cellular signalling network data to reduce the number of genetic signals to a manageable level, prior to statistical analysis, or directly assume  disease-implicated genes; yet these data are known not always  to be reliable.  In this presentation, the speakers describe research aimed at the development of more advanced mathematical, computational and statistical methods, able to handle the complexity, quantity, and imperfections of today's biomedical data, and thereby to bring everyone closer to personalised medicine.  

 



Contact name: Julie Reason
Email: glord-pa@kcl.ac.uk
Tel: 020 7188 3053

 

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