STRUCTURE OVERVIEW
Core programme content
- Introduction to Medical Imaging Sciences
- Research Project 1
- Research Project 2.
Indicative non-core content
- Radiopharmacology (30 credits)
- Radiopharmaceutical Chemistry (30 credits)
- Cyclotron Engineering & Nuclear Chemistry (30 credits)
- Radiopharmaceutical & Regulatory Issues in Nuclear Medicine (15 credits)
- Scientific Basis of Nuclear Medicine (15 credits)
- Diagnostic Nuclear Oncology & Radionuclide Therapy (15 credits)
- Medical Imaging with Non-ionising Radiation (15 credits)
- Medical Imaging with Ionising Radiation (15 credits)
- Computational Methods in Medical Imaging (15 credits)
- Practical Neuroimaging (30 credits).
FORMAT AND ASSESSMENT
Taught modules are presented in a variety of formats, including lectures, workshops, laboratory practicals, site visits etc. Assessment is based on coursework and examination.
Both research projects are carried out under the supervision of academics within the Division’s five departments (Biomedical Engineering; Cancer Imaging; Cardiovascular Imaging; Imaging Chemistry and Biology and Perinatal Imaging and Health). Some research projects may take place in a collaborating laboratory elsewhere in King's or at a collaborating institution.
MODULES
More information on typical programme modules.
NB it cannot be guaranteed that all modules are offered in any particular academic year.
Module code: 7MIGEP14
Credit level: 7
- To provide the fundamentals of radiopharmaceutical science, nuclear chemistry and show its application in the design and formulation of radiopharmaceuticals
- To give an overview and appreciation of radiation dosimetry and hazards and their control
- To provide a fundamental understanding of current imaging modalities and functional, molecular and cellular imaging.
- To provide students with a detailed knowledge and understanding of research methods that are relevant to Imaging Sciences.
- To provide students with the necessary skills to critically appraise published literature on imaging research techniques and findings.
- To provide students with the skills and knowledge to appraise the latest advances in scientific scholarship and the needs of the community in the area of Imaging Sciences.
- To provide students with an understanding of the current regulatory framework required for translational imaging research
- To prepare a foundation for more detailed studies of radiopharmaceutics and radiochemistry topics for subsequent modules.
Module code: 7MIGEP16
Credit level: 7
Module code: 7MIGEP13
Credit level: 7
The aims of the module are to introduce students to the mathematical methods used in medical imaging, as well as to provide a collection of basic code, most likely in Matlab, which can be used to perform the main image reconstructions.
Module code: 7MISR04A
Credit level: 7
The aims of this course are to
- To explain the design and operation of cyclotrons and targets
- To explain the theory of nuclear reactions taking place in cyclotrons and nuclear reactors, and the decay processes of radionuclides
- To describe the production routes to key medical radionuclides
- To engender awareness of the importance of radiation protection and GMP issues
- To provide hands on experience of radionuclide production in a commercial or academic or hospital cyclotron
Module code: 7MIGMP04
Credit level: 7
This course provides students with an understanding of the basic principles of radionuclide therapy, radiation protection and radiation biology.
The course will include training in the protection requirements of clinical practice in thyroid cancer, neuro-endocrine tumours, bone metastases, benign joint disease, radio-immuno and radio-peptide therapy through a programme of lectures, tutorials and demonstrations. The students will acquire the knowledge necessary to undertake radionuclide therapy in a safe and appropriate manner.
Module code: 7MIGMP02
Credit level: 7
This course will describe the scientific basis of radiopharmacy and its application to nuclear medicine functions in the UK. Health and safety legislation and the regulatory bodies concerned with radioactive materials will also be covered. On completion of the course, students will have an understanding of the principles of radiopharmaceutical design, an appreciation of the practical aspects of radiopharmacy operation and a knowledge of regulatory control in nuclear medicine. Assessment is by written examination and coursework.
Module code: 7MISR03A
Credit level: 7
The aims of this course are:
- To show how positron, gamma and particle emitting radiopharmaceuticals are designed, synthesized and analysed, in relation to the properties of the radionuclide and the biological target
- To show how the components of radiopharmaceuticals (organic precursors, chelating agents, biological molecules especially proteins and peptides, radionuclides) are synthesized and analysed
- To provide detailed knowledge of the analytical methods used to characterize precursors and radiopharmaceuticals in terms of structure, labelling efficiency, stability
- To provide opportunity to gain hands-on experience with the above synthetic and analytical methods
- To show the importance of interdisciplinary collaboration to achieve advances in radiopharmaceutical design and clinical use
- To engender an appreciation of the importance of Good Manufacturing Practice in the production of radiopharmaceuticals
- To illustrate the R&D process leading to clinical application of radiopharmaceuticals
- To encourage literature searching and literature awareness
Module code: 7MISR03B
Credit level: 7
The aims of this course are to:
- To show how positron, gamma and particle emitting radiopharmaceuticals are designed, synthesized and analysed, in relation to the properties of the radionuclide and the biological target;
- To show how radiopharmaceuticals are formulated, radiolabelled and analysed;
- To provide detailed knowledge of the analytical methods used to characterize radiopharmaceuticals in terms of purity, labelling efficiency, stability;
- To provide opportunity to gain hands-on experience with radio analytical methods;
- To show the importance of interdisciplinary collaboration to achieve advances in radiopharmaceutical design and clinical use;
- To deliver a detailed theoretical and practical knowledge of Good Manufacturing Practice in the production of radiopharmaceuticals;
- To encourage literature searching and awareness.
Module code: 7MISR04B
Credit level: 7
- To provide knowledge of specific classes of radiopharmaceuticals in clinical use
- To engender interdisciplinary awareness through a series of case studies of the development of selected examples of radiopharmaceuticals from all viewpoints (medical need, biology, physics, chemistry, GMP, radiation protection, patient, cost etc.)
- To exemplify principles taught in Radiopharmacology modules using specific detailed cases
- To provide hands on experience of radiopharmacy work using a work placement in a conventional hospital radiopharmacy
Module code: 7MISPR02
Credit level: 7
The aim of the course is:
- To provide the fundamental principles of radiopharmacology and show their application in the design and formulation of radiopharmaceuticals
- To give an understanding of the biological effects of ionising radiation
- To give an understanding of current research and strategies employed in transport & targeting of radiopharmaceuticals (ADME)
- To provide a rational understanding of radiation dosimetry formalisms and computation methods
- To explore the relations between radiation physics & biology and their practitioners
- To provide an introduction to experimental methods: in vitro and in vivo
- To survey current applications of radiopharmaceuticals and radiotracers in biological & drug research
Module code: 7MIGMP03
Credit level: 7
Assessment:
written examination/s; coursework;
This course will describe the scientific basis of nuclear medicine and its practical application to nuclear medicine. It will also cover the equipment used, statistical methods and the role of computing in the acquisition, processing, display and communication of nuclear medicine studies. On completion of the course, students will have a strong scientific base for the understanding of the practical aspects of nuclear medicine. Assessment is by written examination and coursework.
KEY FACTS
Programme leader/s
Professor Phil Blower; Dr Greg Mullen
Awarding institution
King's College London
Credit value (UK/ECTS equivalent)
UK 180/ECTS 90
Duration
One year FT, September to September
Location
St Thomas’ Campus. Research projects may take place at other locations.
Student destinations
Expected destinations are study for PhD, employment (research or service) in the NHS and commercial nuclear medicine services, the pharmaceutical or medical engineering industry.
Year of entry 2013
Offered by