Experimental Biophysics & Nanotechnology

DESCRIPTION

Research is concerned with the development and application of advanced photonic and scanning probe techniques and of novel nanomaterials. The research interests are centred around three overarching themes: Functional nanoparticles, Nano- and bio-imaging, Nanophotonics and plasmonics. Areas of current interest include: plasmonic nanostructures; fluorescence, Raman and scanning probe imaging of cells and molecules; nanoparticle biolabels, nanoemulsions and nanoparticles for harsh environments. There is a particular focus on nanophotonics and on applications in biomedical sciences.

Strong links exist with the Randall Division for Cell and Molecular Biophysics and with the Imaging Sciences Division in the Health Schools in the College. The Group members belong to the KCL Centre for Biophotonics http://www.kcl.ac.uk/research/groups/ biophotonics, the Optical Proteomics consortium http://www.opticalproteomics.org and the KCL Medical Engineering Centre. The Group leads the UK EPSRC research programme on Active Plasmonics www.activeplasmonics.org.



Associated research programmes

Associated staff research interests
Interests:
Research interests: novel x-ray sources, including microfocus, laser-plasma, transition radiation and high-harmonic generation through extreme non-linear processes; diffractive and reflective x-ray optics and their combinations, including multilayers and adaptive systems; applications of x-rays in radiobiology, cultural heritage and the materials and environmental sciences; the development of cosmic-ray detectors.

Current research: studies of radiation-induced cancers; microspectroscopy of wood-based materials aimed at reducing the environmental impact of their production; studies of wood-based cultural heritage objects for conservation, preservation and restoration; understanding the origins of ultra-high-energy cosmic rays using detectors based in local schools.
Tel:
020 7848 2811
Fax:
020 7848 2420
Email:
Website:
Interests:
Research interests: near-field and nano- optics; scanning probe microscopy; nanophotonics and plasmonics; nonlinear optics and spectroscopy; surface plasmons and polaritons; nanostructured metals; optical properties of surfaces, thin films, semiconductors and low-dimensional structures.

Current research: active plasmonic devices and nonlinear metamaterials, plasmonic nanophotonics, nonlinear nano-optics, quantum plasmonics, bio- and chemical sensing with plasmonics.
Website:
Interests:
Research interests: nanophotonics and plasmonics; surface enhanced fluorescence and surface enhanced Raman scattering (SERS); scanning probe microscopy; fluorescence microscopy; coherent anti-Stokes Raman scattering (CARS) microscopy; cell and tissue imaging.

Current research: understanding and exploiting the enhancement of fluorescence emission and decay with plasmonic nanostructures; single molecule imaging; the development of CARS microscopy and its application to cells and tissue.
Tel:
020 7848 2753
Fax:
020 7848 2420
Email:
Website:
Interests:
Research interests: nano- optics; non-linear optics; ultrafast optical spectroscopy; scanning probe microscopy; nanoscale materials; hybrid materials; excitonic materials; plasmonics.

Current research: active plasmonics, nonlinear nano-optics, ultrafast nano-optics, near-field optics.
Tel:
020 7848 2573
Email:
Website:
Interests:
Research interests: fluorescence lifetime imaging (FLIM), time-resolved fluorescence anisotropy imaging (tr-FAIM), fluorescence spectroscopy, time-correlated single photon counting (TCSPC), photon counting imaging

Current research: diffusion studies of labelled drugs and proteins in cells using FRAP and tr-FAIM, FLIM and FAIM of fluorescent molecular rotors, imaging of nanoparticles in cells, photon counting imaging with an image intensifer or an electron-bombarded CCD
Website:
Interests:
Organometallic based synthesis of semiconductorand metal nanoparticles, biological applications of nanomaterials, rare-earth based nanomaterials
Tel:
020 7848 2121
Fax:
020 7848 2420
Email:
Website:
Interests:
Research interests: Miniaturisation and integration of biological materials into technical systems; scanning-probe techniques beyond topographic imaging; physical properties of biological materials; biocompatible micro- and nanopatterning.

Current research: Miniaturisation by microdroplets; mechanics of protein fibrils; electrical force microscopy.
Tel:
020 7848 2592, 020 7848 2241
Fax:
020 7848 2932
Email:
Website:
Interests:
Research interests: nano-optics; photonic networks; lasing; nanophotonics and plasmonics; quantum optics and quantum plasmonics; nonlinear optics and spectroscopy; disordered media; collective and critical phenomena; photonic crystals; nano-antennas; nano-structured metals; optical properties of low-dimensional structures.

Current research: complex photonic networks; unconventional lasing; hybrid plasmonic-photonic systems; quantum plasmonics; Anderson localisation.
Email:
Website:
Interests:
Research interests: nanoparticles and nanocomposite materials; sintering of nanoparticle materials; electronic materials for interconnections in harsh environments; solder materials; adhesives; electromigration; rheology; transition metal oxide materials and their use as diodes and radiaton detectors.

Current research: reactive micro- and nano- scale particles for modifying chemical properties of solders; electromigration in thin films; sintering of Cu and Ag nanoparticles.

Tel:
020 7848 1780
Fax:
020 7848 2932
Email:
Website:
Interests:
Research interests: scanning probe microscopy; single molecules; single molecule force spectroscopy; force-clamp spectroscopy, biophysics; protein folding; mechanochemistry; lipid bilayers; surface science; nanomechanics; thin films; wetting.

Current research: conformational dynamics of single molecules under force; protein folding; single molecule force-clamp spectroscopy; protein folding; the effect of a mechanical force on the energy landscape of a chemical reaction at the single bond level; nanomechanics of lipid bilayers; tribology.
Tel:
020 7848 7106
Email:
Website:
Interests:
Research interests: Colloids and Surface Science, Emulsion science and technology, Polymerisation in aqueous media, Nanoparticles, Drug delivery, and Microfluidics.

Current research: Polymeric and hybrid nanoparticles, Core-shell particles, Nanoemulsions, Multiple emulsions, and Microfluidic generation of uniform complex drops and particles.
Website:
CONTACTS FOR FURTHER INFORMATION
Dr Sergi Garcia-Manyes, Dr Mark Green, Prof. Samjid Mannan, Dr Patrick Mesquida, Prof. David Richards, Dr Shariar Sajjadi-Emami, Dr Klaus Suhling, Prof. Anatoly Zayats, Dr Gregory Wurtz or the Postgraduate Student Officer, tel 020 7848 2155, fax 020 7848 2420
Email
Website