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Much of this work is carried out with patients at the National Affective Disorder Unit, part of South London and Maudsley NHS Foundation’s Trust National Division. Patients from across the country are referred to this service with treatment resistant depression, seasonal affective disorder and manic depression. Dr Anthony Cleare, who heads the Section of Neurobiology of Mood Disorders, also runs the inpatient unit of the Affective Disorders Unit, based at Bethlem Royal Hospital in Kent.
The research team uses a variety of techniques to investigate neurobiological changes in mood disorders and looks at the role of hormones and the link between the brain and the immune system within a research laboratory based in the National Affective Disorder Unit. The team also measures brain function using Magnetic Resonance Imaging machines at the Centre for Neuroimaging Sciences, jointly run by the IoP and SLaM. One collaborative neuroimaging study being carried out with this Centre is seeking to predict the response of patients with depression to medication by measuring reactions in the brain. This drug development project is funded by Glaxo Smith Kline.
The Section focuses on two other areas of research: Chronic Fatigue Syndrome (CFS/ME) and the health effects of mobile phones. Both these tranches of research are carried out in collaboration with the Section of General Hospital Psychiatry, also within the Division of Psychological Medicine and Psychiatry.
Research into the contribution of neuroendocrinological and other neurobiological factors in CFS/ME is conducted with the Chronic Fatigue Research and Treatment Unit, a national specialist service run jointly by King’s College Hospital NHS Foundation Trust and the Section of General Hospital Psychiatry. Collaborative ongoing work with the Mobile Phone Research Unit in General Hospital Psychiatry is looking at the reasons for sensitivity to mobile phones, including police radios, and the potential effects of mobile phone radiation on neuroendocrine systems. This work is funded by the Mobile Telecommunications and Health Research programme.
Other funders of research include NARSAD (The Mental Health Research Association) and the Biomedical Research Centre for Mental Health, based at the IoP and SLaM.
Dr Anthony Cleare is a Reader in Affective Disorders who trained in psychiatry at The Maudsley Hospital. Any potential PhD students interested in undertaking research in the Section should contact him, a.cleare@iop.kcl.ac.uk.
The Section of Neurobiology of Mood Disorders is in the Department of Psychological Medicine with the Division of Psychological Medicine and Psychiatry.
Section of Neurobiology of Mood Disorders
Division of Psychological Medicine and Psychiatry, PO74
Institute of Psychiatry
De Crespigny Park
London SE5 8AF
Contact: Dilys Baker
Email: dilys.baker@kcl.ac.uk
Phone: 020 7848 5130
Fax: 020 7848 5408
Section of Neurobiology of Mood Disorders
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DESCRIPTION
The Section works to understand more about the neurobiological causes of mood disorders (also known as affective disorders), mental illnesses where the normal functioning of mood is disrupted, including clinical depression and bipolar disorder.Much of this work is carried out with patients at the National Affective Disorder Unit, part of South London and Maudsley NHS Foundation’s Trust National Division. Patients from across the country are referred to this service with treatment resistant depression, seasonal affective disorder and manic depression. Dr Anthony Cleare, who heads the Section of Neurobiology of Mood Disorders, also runs the inpatient unit of the Affective Disorders Unit, based at Bethlem Royal Hospital in Kent.
The research team uses a variety of techniques to investigate neurobiological changes in mood disorders and looks at the role of hormones and the link between the brain and the immune system within a research laboratory based in the National Affective Disorder Unit. The team also measures brain function using Magnetic Resonance Imaging machines at the Centre for Neuroimaging Sciences, jointly run by the IoP and SLaM. One collaborative neuroimaging study being carried out with this Centre is seeking to predict the response of patients with depression to medication by measuring reactions in the brain. This drug development project is funded by Glaxo Smith Kline.
The Section focuses on two other areas of research: Chronic Fatigue Syndrome (CFS/ME) and the health effects of mobile phones. Both these tranches of research are carried out in collaboration with the Section of General Hospital Psychiatry, also within the Division of Psychological Medicine and Psychiatry.
Research into the contribution of neuroendocrinological and other neurobiological factors in CFS/ME is conducted with the Chronic Fatigue Research and Treatment Unit, a national specialist service run jointly by King’s College Hospital NHS Foundation Trust and the Section of General Hospital Psychiatry. Collaborative ongoing work with the Mobile Phone Research Unit in General Hospital Psychiatry is looking at the reasons for sensitivity to mobile phones, including police radios, and the potential effects of mobile phone radiation on neuroendocrine systems. This work is funded by the Mobile Telecommunications and Health Research programme.
Other funders of research include NARSAD (The Mental Health Research Association) and the Biomedical Research Centre for Mental Health, based at the IoP and SLaM.
Dr Anthony Cleare is a Reader in Affective Disorders who trained in psychiatry at The Maudsley Hospital. Any potential PhD students interested in undertaking research in the Section should contact him, a.cleare@iop.kcl.ac.uk.
The Section of Neurobiology of Mood Disorders is in the Department of Psychological Medicine with the Division of Psychological Medicine and Psychiatry.
Section of Neurobiology of Mood Disorders
Division of Psychological Medicine and Psychiatry, PO74
Institute of Psychiatry
De Crespigny Park
London SE5 8AF
Contact: Dilys Baker
Email: dilys.baker@kcl.ac.uk
Phone: 020 7848 5130
Fax: 020 7848 5408
Associated research programmes
CONTACTS FOR FURTHER INFORMATION
Anthony Cleare, tel 020 7848 5130
Email
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