Neuroscience

• Number of academic staff: 15.
• Number of research students: 23.

Our research explores the cellular and molecular basis of neurodegenerative and neurodevelopmental disorders including Alzheimer's Disease, Parkinson's disease, Huntington's disease, Batten Disease, motor neuron disease, schizophrenia, depression and autism spectrum disorder. Within this brief, we focus on using stem cells and patent specific induced pluripotent stem cells and use these as models to unravel transcriptional, epigenetic and signalling regulatory mechanisms responsible for formation and maintenance of neurons and astrocytes and also as transplantation tools to restore function lost in neurodegeneration and stroke. We also use both fly and rodent models to investigate the molecular basis of learning and memory and the loss of synaptic plasticity in disorders such as Alzheimer's Disease.