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Translational Cancer Medicine MRes

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Overview

Translational Cancer Medicine enables you to gain detailed knowledge and understanding of research methods applied to rational drug design, clinical study design, molecular and cell biology, tumour immunology, genetics and cancer imaging. You'll gain practical experience  through two six-month laboratory rotations.

 


Key benefits

  • A unique research programme that includes the study of advanced imaging methods.
  • The sponsoring laboratories and departments all have international standing and closely supervise research trainees throughout the study programme.
  • Recently released data from the Higher Education Funding Council for England (Hefce) shows that King’s College London is equal top in England (with Queen Mary, University of London) for its PhD completion rates. This programme will potentially select candidates for the PhD programme within the Division of Cancer Studies

Key information

Application status Open

Duration One year FT, September to September

Study mode Full-time

Credit value UK 180/ECTS 90

Course intake 10-14 FT

Course leaders

Prof Tony Ng, Programme Director

dora.jonsdottir@kcl.ac.uk

Course contact for further information

Postgraduate Admissions Team, Admissions Office tel: +44 (0) 20 7848 7000 fax: +44 (0) 20 7848 7200

Course contact form Postgraduate admissions enquiry form

Awarding institution King's College London

Faculty Faculty of Life Sciences & Medicine

Department

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Entry requirements & how to apply


Visit our admissions webpages to view our English language entry requirements.

First class or high 2:1 BSc (honours) degree or overseas equivalent in biomolecular or physical sciences. MBBS students can be admitted at any time following the third year of their programme. Post-year three: entry is based on year three performance plus evidence of knowledge of the basic elements of translational research topics. Advanced years (four to five): students must complete their current year of study. External students need to obtain permission from their own medical school and provide evidence of their exam performance in the pre-clinical examinations.

Application procedure

Applications are made on-line. To apply, please select the 'Apply' button at the top right of this page. Applications are subject to a £50 non-refundable application fee. 

Personal statement and supporting information

Please detail your research experience and any previous laboratory experience. Include your reason for applying and career aims. Please specify two areas of interest from the list of projects in the description. MBBS students should provide a statement demonstrating knowledge of basic elements of translational research topics such as epidemiology, clinical biostatistics and clinical pharmacology (relating to drug discovery).

Application closing date

The deadline for applications for September 2017 entry is 31st March 2017. After this date, programmes will remain open if places are available, and programmes will be closed as soon as they are full, so we encourage you to submit your application as soon as possible. For programmes with spaces remaining, no further applications will be accepted from non-EU (Overseas) nationals after 30th July 2017 or from UK/ EU nationals after 3rd September 2017.

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Course detail

Description

The Translational Cancer Medicine MRes study pathway offers unique opportunities for you to join experienced research teams and work on particular projects from the outset. This course will allow you to develop an in-depth understanding of research methods, and of how theoretical academic studies and skills relate to research projects.

Initially, you will explore Fundamentals of Translational Cancer Medicine, providing you with advanced knowledge and skills to conceptualise, design, conduct and critically appraise specialist research. You will then complete two six-month research modules, which are worth 75 credits each.

Research projects include

 

Discipline

Supervisor

Project title

Cancer Biostatistics & Epidemiology

Dr Mieke Van Hemelrijck

Serum biomarkers and risk of cancer in the Swedish AMORIS dataset -
  data on 800,000 men and women

Cancer functional genomics, computational biology

Dr Francesca Ciccarelli

Validation of actionable genes in colorectal cancer

Cancer Cell Biology

Prof Anne Ridley

Targeting Rho signalling networks in cancer invasion and metastasis

Cancer Cell Biology

Dr James Arnold

Tumour associated macrophages in cancer progression

Cancer Cell Biology

Dr Jeremy Carlton

Regulation of cell division and receptor degradation by
  the ESCRT-machinery 

Cancer Cell Biology

Dr Gilbert Fruhwirth

Multi-modal in vivo imaging for monitoring cancer treatment

Cancer Cell Biology & Imaging

Prof Tony Ng

cMet/ErbB and exosomes in non-small cell lung cancer

Imaging

Prof Vicky Goh &
  Prof Gary Cook

Optimising multimodality treatment response assessment with imaging

Cancer Oral

Prof Fiona Watt &
  Dr Ines Sequeira

Mouse knockout screen for genes that control skin fibroblast lineages

Cancer Head/Neck

Prof Mahvash Tavassoli

Predictive Biomarkers of Treatment Resistance in Head
  and Neck Squamous Cell Carcinoma

Molecular Pathology

Prof Sarah Pinder

Molecular pathology of breast cancer precursors

Haemato-oncology

Prof Farzin Farzaneh &
  Dr Kiki Ioannou

High throughput analysis of modulators of cellular immunity against   cancer associated antigens

Haemato-oncology

Dr Andrea Pepper &
  Dr Eve Coulter

Project to be confirmed

Haemato-oncology

Dr Alan Ramsay

Investigating the tumour microenvironment (TME) and immune suppression   in lymphoma

Haemato-oncology

Prof Francesco Dazzi

Tumour associated stroma and therapeutic targets

Haemato-oncology

Prof Ghulam Mufti

Truncal vs branch mutations in MDS/AML

Haemato-oncology

Prof Ghulam Mufti

Immune response in aplastic anaemia

Tumour Immunology

Prof Joy Burchell

Changes in post-translational modifications (O-linked glycosylation)   of breast cancer: The effect on tumour behaviour and immune recognition

Tumour Immunology

Prof Tony Ng

Investigations of the impact of EGFR/HER3 treatments on the cancer:   immune stromal microenvironment interface

Tumour Immunology

Dr Debashis Sarker &
  Dr James Spicer

Factors affecting patient recruitment and experience in Phase 1 trials

Tumour Immunology

Dr John Maher

Genetic targeting of T-cells against cancer

Research Oncology

Dr Elinor Sawyer

Identification of genes that predispose to lobular breast cancer

Research Oncology

Dr Anita Grigoriadis

Molecular characterisation of lymph nodes

Stem Cells and Bone Cancer

Prof Agamemnon Grigoriadis

Targeting FGFR signalling in bone tumour growth and metastasis

 

 

 

Further literature

https://www.kcl.ac.uk/study/postgraduate/apply/enquiry-form.aspx

Course format and assessment

Teaching

We use lectures, seminars and group meetings to deliver most of the modules on the programme. You will also be expected to undertake a significant amount of independent study.

On average teaching consists of:

  • 52 hours of lectures
  • 1.5 – 3 hours per week of Lab/group meetings (depending on projects)
  • Feedback: One hour per semester.

Throughout the year, you will also attend literature reviews and journal clubs that the labs/departments organise, as well as any other internal or external seminars deemed relevant to your projects/assignments.

Assessment

The primary method of assessment for this course is a combination of written essays, a thesis (research report), a presentation/Q&A session regarding the research report and a draft of a scientific paper.

Extra information

Occupational health clearance will be required for some of the projects.

Structure

  • Required Modules

    • Fundamentals of Translational Cancer Medicine (30 credits)
    • Laboratory Based Research Project 1 (75 credits)
    • Laboratory Based Research Project 2 (75 credits)

    We regularly review our modules to make sure our programmes are as up-to-date, innovative and relevant as possible. The modules we offer may therefore change. We suggest that you check the course finder for updates: http://www.kcl.ac.uk/study/postgraduate/index.aspx

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Career prospects

Future PhD studies. Clinical and non-clinical academic careers in cancer medicine.

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Fees and funding

Full time tuition fees - Home/EU

£10,950 p.a. (2017/18)*

Full time tuition fees - Overseas

£22,800 p.a. (2017/18)

*These tuition fees may be subject to additional increases in subsequent years of study, in line with King’s terms and conditions.

Please note: Current regulations allow some students to pay UK tuition fees on the basis of their EU citizenship or residency. Until these eligibility criteria are changed, the EU tuition fee will remain the same as the UK tuition fee. 

Deposit

When you receive an offer for this course you will be required to pay a non-refundable deposit to secure your place. The deposit will be credited towards your total fee payment.

The UK/EU deposit is £500.

The INTERNATIONAL deposit is £2,000. 

  • If you receive an offer on or before 31st March 2017, payment is due by 30th April 2017.
  • If you receive an offer between 1st April 2017 and 30th June 2017, payment is due within one month of receiving the offer.
  • If you receive an offer between 1st July 2017 and 31st July 2017, payment is due within two weeks of receiving the offer.
  • If you receive an offer on or after 1st August 2017, payment is due within one week of receiving the offer.

 Please visit our web pages on fees and funding for more information.

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Next steps

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