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MRC UKRI Health Data Research UK Clinical Fellow
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PhD Student and Researcher
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MRC Research Fellow and Honorary Lecturer
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Teaching Fellow in Organisational Psychiatry & Psychology
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MRC Clinical Research Training Fellow
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Postdoctoral Research Associate
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Business Manager, Department of Psychosis Studies
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Professor of Psychiatry & Systems Neuroscience
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Research Worker
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Clinical Senior Lecturer in Early Detection & Intervention
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PhD Student
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Research Assistant
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Senior Lecturer in Psychosis Studies
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NIHR Maudsley BRC Research Fellow and Honorary Lecturer Senior Clinical Psychologist
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Lecturer in Organisational Psychiatry & Psychology
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Events Co-Ordinator
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Trial Coordinator
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Professor of Cognitive Psychopathology
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Senior Administrator, Department of Psychosis Studies
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Head of Administration, School of Academic Psychiatry
Click here for a full list of people associated with this department
The Cognition, Schizophrenia and Imaging Laboratory (CSI Lab) at the Institute of Psychiatry, Psychology & Neuroscience seeks to understand the core biological mechanisms responsible for the development and symptoms of psychotic illness.
The acute effects of cannabis use: An escalating THC dose-finding pilot study in frequent cannabis users
We are a multi-disciplinary group of researchers based at the Institute of Psychiatry, Psychology & Neuroscience (King's College London). We develop and apply state-of-the-art machine learning methods to investigate a range of mental health disorders, with a particular focus on psychosis. A core aim of our research is to develop and validate clinical tools that could be used to inform diagnosis and treatment of individual patients.
We use state-of-the-art brain imaging techniques in humans and animal models to investigate the neural mechanisms involved in emotions, and their role in the development of psychotic disorders such as schizophrenia.
We aim to understand the biological and cognitive mechanisms underlying schizophrenia, bipolar and related disorders to develop better treatments.
The aim of the PSYSCAN project is to improve the care of patients with psychiatric disorders, specially, schizophrenia. This goal will be achieved by developing a neuroimaging-based tool which will help physicians in a clinical setting to resolve key clinical issues in the management of patients with psychotic disorders
People with schizophrenia suffer from a range of symptoms including hallucinations (such as hearing voices), delusions (false beliefs) and thought disorder (thoughts not flowing in a logical way).
Urban Mind is an app that measures your experience of urban & rural living in the moment.
YoungSpace is a group of researchers from the Institute of Psychiatry, Psychology & Neuroscience. We are committed to improving the life quality of young people struggling with mental health issues through high-quality research.
Mechanisms underlying treatment response in psychosis (MUTRIPS)
MUTRIPS in a European Research Council funded project which aims to identify the neural mechanisms underlying antipsychotic treatment response in psychosis. The key hypothesis is that lack of adequate response to treatment, the persistence of symptoms despite optimal contemporary treatment, is characterised by a failure of prefrontal cognitive control mechanisms, specifically in modulation of feedback learning.
Find out more about MUTRIPS
DFEND
A randomised, double blind, placebo controlled parallel group trial of vitamin D supplementation compared to placebo in people presenting with their First Episode of psychosis Neuroprotection Design.
The aim of this study is to investigate the effects of vitamin D supplementation in people presenting with their first episode of psychosis.
Contact: Dr. Gabriella Wojewodka: gabriella.wojewodka@kcl.ac.uk
Further information: Trial registration
eCBD, reducing the harmful effects of cannabis use: Finding the optimal CBD:THC ratio.
In this randomised, double-blind experimental study, healthy volunteers will attend 4 experimental sessions in which they will be administered inhaled cannabis, with each session involving a different CBD:THC ratio. The cannabis ratios will be 0:1, 1:1, 2:1 and 3:1 CBD:THC. The aim of this study is to explore at what relative dose ratio the harmful effects of THC on cognition and psychopathology are reduced by CBD.
Investigators:Professor Philip McGuire, Professor Sir Robin Murray, Dr Amir Englund, Dr Tom Freeman, Mr Dominic Oliver, Mr Jack Wilson, Dr Edward Chesney
Contact:
eTHC
In this randomised, double-blind, dose-finding experimental study, frequent problematic cannabis users will attend 3 experimental sessions, in which they will be administered inhaled cannabis, with each session involving a different THC dose. The doses will be 10, 20, and 30mg of THC. The aim of the present preliminary study is to determine which dose of THC induces subclinical paranoid ideations and/or cognitive impairments in frequent cannabis users.
Find out more about eTHC
Emotion circuit-based studies of the extended psychosis phenotype
We use neuroimaging methods and behavioural assays to characterise the neural correlates of social and emotional information processing across the psychosis spectrum (schizotypy, clinical high risk of psychosis, first-episode psychosis).
Find out more about this project
Neurodevelopment and Mental Health
Psychotic disorders may result from perturbations at an early stage in development. Studies in people who are born very preterm provide a powerful way of examining the effects of this on cognitive function and mental health in later life. Our department has conducted a series of prospective studies using neuroimaging, neuropsychology and clinical assessments in a large cohort of people who were born preterm and are now entering adulthood.
Contact: Dr Chiara Nosarti chiara.nosarti@kcl.ac.uk
16 November 2022
New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College…
23 November 2020
Several colleagues working across IoPPN and South London & Maudsley NHS Foundation Trust (SLaM)…
13 October 2020
We are pleased to welcome Professor Nikos Koutsouleris as the new Chair of Precision Psychiatry with…
24 June 2020
Problems in how the brain recognizes and processes novel information lie at the root of psychosis,…