Principal Investigator: Professor Martyn T. Cobourne
Basic science research: The Cobourne Laboratory is primarily focussed on further understanding Hedgehog signalling during early craniofacial development. In particular, the Sonic hedgehog pathway and its role in human craniofacial malformations.
Clinical research: We also maintain an active clinical research group investigating evidence-based orthodontics and in particular, the efficiency of orthodontic treatment strategies using multicentre randomised controlled trials.
Chen-ming Fan (Carnegie Institute of Washington)
Laurent Viriot (Institute of Functional Genomics, Lyon)
We also have significant departmental collaborations with:
Prof Jeremy Green investigating cellular morphogenesis in early tooth and palate development
Dr Karen Liu investigating Hedgehog signalling in tongue development
Dr Cynthia Andoniadou investigating Wnt signalling in tooth development
Professor Paul Sharpe investigating the genetics of supernumerary tooth formation
Andrew DiBiase (East Kent NHS Foundation Trust)
Farhad Naini (St George’s NHS Foundation Trust)
Spyridon Papageorgiou (University of Bonn)
Melita Irving (GSTT NHS Foundation Trust)
Tel: +44 (0)20 7188 4432