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Francis-West Lab

Francis-West Lab

Principal InvestigatorProfessor Philippa Francis-West

 

Mechanisms of vertebrate morphogenesis

The Francis-West Laboratory studies the function of Dchs1-Fat4-PCP and Hippo signalling during development to understand how these pathways control the shape and development of embryonic structures through the regulation of cell migration, proliferation, survival  and differentiation. This research has relevance to understanding birth defects and Van Maldergem and Hennekam syndromes. The group are currently focused on the development of the craniofacial complex, branching morphogenesis and neuronal migrations. Our work is currently funded by the BBSRC and EU.

 

Key collaborators:

Professor Kenneth Irvine, HHMI, Rutger’s University, New Jersey, USA

Professor Andrew Pitsillides, Royal Veterinary College, London

Professor Jamie Davies, University of Edinburgh

Dr Francois Guillemot, Crick Institute London

Dr Eileen Gentleman, Department of Craniofacial Development and Stem Cell Biology, King's College London

Dr Isabelle Miletich, Department of Craniofacial Development and Stem Cell Biology, King's College London

Dr Cynthia Andoniadou, Department of Craniofacial Development and Stem Cell Biology, King's College London

 

Contact information:

Email: Philippa.francis-west@kcl.ac.uk 

Tel: +44 (0)20 7188 1803 

 

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