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Direct dental cell reprogramming for tooth regeneration

*Please note, this project is self-funded*

Project details

Supervisor: Professor Paul Sharpe

Duration: Four years

Funding: Self-funded

Application deadline: Open until suitable candidate is found

Reference number: 2017/DI/08 

Project description

When dentine and underlying odontoblasts are damaged, a repair process is initiated that involves the recruitment of cells from the pulp. We have identified a specific cell homing process whereby the progeny of mesenchymal stem cells migrate towards sites of tooth damage.

Project aim

To identify the signalling pathways that act to recruit dental mesenchymal stem cells to sites of tissue damage.

To view entry requirements and further course information, see the Dental and Health Sciences Research MPhil/PhD

Next steps

How to apply

Please apply online at following these steps:

  1. Register a new account/login
  2. Once logged in, select Create a new application
  3. Enter ‘Dental and Health Sciences Research MPhil/PhD (Full-time/Part-time)' under Choose a programme. Please ensure you select the correct mode of study
  4. Select a start date from the list under Entry requirements on this webpage.

Please note: Applicants must include the project reference number in the 'Research proposal' section of the application.

Contact for further information

Professor Paul Sharpe (

Related division Craniofacial Development and Stem Cell Biology.

Back to Research Projects main page.

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