Investigation of the effect of host genetic variants on subgingival microbes and gingival inflammation in gingivitis and periodontitis
Project details
First supervisor: Professor Luigi Nibali
Second supervisor: to be confirmed
Sponsor: Unilever/ BBSRC
Funding available: £18,500 stipend + £6,000 bench fees/year
Duration of award: 3-4 years
Mode of study: Full-time
Eligibility: UK
Start date: 1 October 2020
Application deadline: 26 January 2020
Reference number: 2019/DOCS/08
Project description
Investigation of the effect of host genetic variants on subgingival microbes and gingival inflammation in gingivitis and periodontitis
Periodontal Infectogenomics studies how host genetic variants can affect the composition of the subgingival biofilm.
The aim of this PhD is to test the effect of specific host genetic variants on periodontal inflammation and microbial growth in gingivitis and periodontitis.
This PhD will be based on a clinical trial on experimental gingivitis in patients with different host genetic variants identified as predisposing to ‘gingival hyper-inflammation’. Identified genetic variants and microbes will be tested in replication cohorts.
Research training
Genetics/ microbiology/periodontology
To view entry requirements and further information, see the Dental and Health Sciences Research MPhil/PhD.
Next steps
Please apply online at apply.kcl.ac.uk following these steps:
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Register a new account/login
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Once logged in, select Create a new application
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Enter ‘Dental and Health Sciences Research MPhil/PhD (Full-time)/(Part-time)' under Choose a programme. Please ensure you select the correct mode of study
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Select 1 October 2020 as the start date
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Please note: Applicants must include the project reference number ( 2019/DOCS/08) in the 'Research proposal' and 'Funding (point 5)' sections of the application.
Applications must be received by the deadline specified in this listing.
Applicants are strongly encouraged to discuss projects with the first supervisor prior to submitting an application.
Contact for further information
Professor Luigi Nibali
luigi.nibali@kcl.ac.uk
Related Centre Centre for Host-Microbiome Interactions
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