Mechanisms and Consequences of Cardiovascular Stiffening: Drilling down on different Scales

FOR INTERNAL KCL STAFF AND STUDENTS ONLY

Programme

13.30-13.45 Registration

13.45-13.50 Cathy Shanahan - Opening remarks

13.50-14.05 Pier Giorgio / Pablo Lamata - Deep mechanical phenotyping by advanced imaging and modelling

14.05-14.20 Marina Cecelja - Exploiting UKBB to understand common genetic aetiology of cardiac/vascular stiffening

14.20-14.35 Elisabetta Brunello - Regulation of the heartbeat by the myosin filament

14.35-14.50 Elisabeth Ehler - The intercalated disc - a mechanosensing signalling node in dilated cardiomyopathy?

14.50 – 15.10 tea/coffee

15.10-15.25 Susan Cox – TBC

15.25-15.40 Sergi Garcia-Manyes – The mechanical stability of proteins regulates their translocation rate into the cell nucleus

15.40 -15.55 Kate Spillane - TBC

15.55-16.10  Jody Rosenblatt - Epithelial cell extrusion

16.10-16.25 tea coffee

16.25-16.30 Eileen Gentleman - Modifiable 3D biomaterials for tissue and disease modelling

16.30-16.35 Franca Fraternali - TBC

16.35-16.40 Tanya Shaw - Altered protein composition in pathological keloid scars – what are the cellular and biomechanical implications?

16.40 -16.45 Brian Stramer - Mechanisms of extracellular matrix remodelling during tissue scarring

16.50 – 17.30 Open discussion and brainstorming on theme 

17.30-18.30 Networking with refreshment