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publications

Publications

Publications resulting from work carried out in the Genomics Centre

2018

Zoupa M, Xavier GM, Bryan S, Theologidis I, Arno M, Cobourne MT. Gene expression profiling in the developing secondary palate in the absence of Tbx1 function. BMC Genomics. 2018 Jun 4;19(1):429. doi: 10.1186/s12864-018-4782-y. PubMed PMID: 29866044; PubMed Central PMCID: PMC5987606

Burr S, Caldwell A, Chong M, Beretta M, Metcalf S, Hancock M, Arno M, Balu S, Kropf VL, Mistry RK, Shah AM, Mann GE, Brewer AC. Oxygen gradients can determine epigenetic asymmetry and cellular differentiation via differential regulation of Tet activity in embryonic stem cells. Nucleic Acids Res. 2018 Feb 16;46(3):1210-1226. doi: 10.1093/nar/gkx1197. PubMed PMID: 29186571; PubMed Central PMCID: PMC5814828.

2017

Mesnage R, Phedonos A, Biserni M, Arno M, Balu S, Corton JC, Ugarte R, Antoniou MN. Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide constituents. Food Chem Toxicol. 2017 Oct;108(Pt A):30-42. doi: 10.1016/j.fct.2017.07.025. Epub 2017 Jul 12. PubMed PMID: 28711546.

Kumar A, Bicer EM, Pfeffer P, Monopoli MP, Dawson KA, Eriksson J, Edwards K, Lynham S, Arno M, Behndig AF, Blomberg A, Somers G, Hassall D, Dailey LA, Forbes B, Mudway I. Differences in the coronal proteome acquired by particles depositing in the lungs of asthmatic versus healthy humans. Nanomedicine. 2017 Nov;13(8):2517-2521. doi: 10.1016/j.nano.2017.06.008. Epub 2017 Jun 22. PubMed PMID: 28647590.

Mesnage R, Phedonos A, Arno M, Balu S, Corton JC, Antoniou MN. Editor's Highlight: Transcriptome Profiling Reveals Bisphenol A Alternatives Activate Estrogen Receptor Alpha in Human Breast Cancer Cells. Toxicol Sci. 2017 Aug 1;158(2):431-443. doi: 10.1093/toxsci/kfx101. PubMed PMID: 28591870; PubMed Central PMCID: PMC5837682.

Mesnage R, Arno M, Costanzo M, Malatesta M, Séralini GE, Antoniou MN. Erratum to: Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure. Environ Health. 2017 Mar 23;16(1):28. doi: 10.1186/s12940-017-0236-2. PubMed PMID: 28335822; PubMed Central PMCID: PMC5364686.

Mesnage R, Arno M, Séralini GE, Antoniou MN. Transcriptome and metabolome analysis of liver and kidneys of rats chronically fed NK603 Roundup-tolerant genetically modified maize. Environ Sci Eur. 2017;29(1):6. doi: 10.1186/s12302-017-0105-1. Epub 2017 Feb 7. PubMed PMID: 28239534; PubMed Central PMCID: PMC5306156.

Nag A, Lu H, Arno M, Iglesias AI, Bonnemaijer P, Broer L, Uitterlinden AG, Klaver CC, van Duijn C, Hysi PG, Hammond CJ. Evaluation of the Myocilin Mutation Gln368Stop Demonstrates Reduced Penetrance for Glaucoma in European Populations. Ophthalmology. 2017 Apr;124(4):547-553. doi: 10.1016/j.ophtha.2016.11.018. Epub 2016 Dec 27. PubMed PMID: 28038983.

2016

Petrova A, Capalbo A, Jacquet L, Hazelwood-Smith S, Dafou D, Hobbs C, Arno M, Farcomeni A, Devito L, Badraiq H, Simpson M, McGrath JA, Di WL, Cheng JB, Mauro TM, Ilic D. Induced Pluripotent Stem Cell Differentiation and Three-Dimensional Tissue Formation Attenuate Clonal Epigenetic Differences in Trichohyalin. Stem Cells Dev. 2016 Sep 15;25(18):1366-75. doi: 10.1089/scd.2016.0156. Epub 2016 Aug 30. PubMed PMID: 27460132; PubMed Central PMCID: PMC5035378.

Arbore G, West EE, Spolski R, Robertson AAB, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann HJ, Cope AP, Mayer-Barber KD, Kemper C. T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells. Science. 2016 Jun 17;352(6292):aad1210. doi: 10.1126/science.aad1210. PubMed PMID: 27313051; PubMed Central PMCID: PMC5015487.

Kumar A, Dailey LA, Swedrowska M, Siow R, Mann GE, Vizcay-Barrena G, Arno M, Mudway IS, Forbes B. Quantifying the magnitude of the oxygen artefact inherent in culturing airway cells under atmospheric oxygen versus physiological levels. FEBS Lett. 2016 Jan;590(2):258-69. doi: 10.1002/1873-3468.12026. Epub 2016 Jan 23. PubMed PMID: 26823171.

Kumar A, Bicer EM, Morgan AB, Pfeffer PE, Monopoli M, Dawson KA, Eriksson J, Edwards K, Lynham S, Arno M, Behndig AF, Blomberg A, Somers G, Hassall D, Dailey LA, Forbes B, Mudway IS. Enrichment of immunoregulatory proteins in the biomolecular corona of nanoparticles within human respiratory tract lining fluid. Nanomedicine. 2016 May;12(4):1033-1043. doi: 10.1016/j.nano.2015.12.369. Epub 2016 Jan 6. PubMed PMID: 26767511.

Fernandes ES, Russell FA, Alawi KM, Sand C, Liang L, Salamon R, Bodkin JV, Aubdool AA, Arno M, Gentry C, Smillie SJ, Bevan S, Keeble JE, Malcangio M, Brain SD. Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner. Arthritis Res Ther. 2016 Jan 11;18:7. doi: 10.1186/s13075-015-0905-x. PubMed PMID: 26754745; PubMed Central PMCID: PMC4718045.

Chapple SJ, Keeley TP, Mastronicola D, Arno M, Vizcay-Barrena G, Fleck R, Siow RCM, Mann GE. Bach1 differentially regulates distinct Nrf2-dependent genes in human venous and coronary artery endothelial cells adapted to physiological oxygen levels. Free Radic Biol Med. 2016 Mar;92:152-162. doi: 10.1016/j.freeradbiomed.2015.12.013. Epub 2015 Dec 15. PubMed PMID: 26698668.

2015

Brooks SE, Bonney SA, Lee C, Publicover A, Khan G, Smits EL, Sigurdardottir D, Arno M, Li D, Mills KI, Pulford K, Banham AH, van Tendeloo V, Mufti GJ, Rammensee HG, Elliott TJ, Orchard KH, Guinn BA. Application of the pMHC Array to Characterise Tumour Antigen Specific T Cell Populations in Leukaemia Patients at Disease Diagnosis. PLoS One. 2015 Oct 22;10(10):e0140483. doi: 10.1371/journal.pone.0140483. eCollection 2015. PubMed PMID: 26492414; PubMed Central PMCID: PMC4619595.

Brown C, Esterhazy D, Sarde A, Pullabhatla V, London M, Arno M, de Rinaldis E, Mucida D, Lord G, Noelle R. Role of retinoic acid in the stability of the T-helper-type 1 lineage and implications for autoimmunity. Lancet. 2015 Feb 26;385 Suppl 1:S25. doi: 10.1016/S0140-6736(15)60340-3. PubMed PMID: 26312847.

Mesnage R, Arno M, Costanzo M, Malatesta M, Séralini GE, Antoniou MN. Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure. Environ Health. 2015 Aug 25;14:70. doi: 10.1186/s12940-015-0056-1. Erratum in: Environ Health. 2017 Mar 23;16(1):28. PubMed PMID: 26302742; PubMed Central PMCID: PMC4549093.

Hoffman E, Kumar A, Kanabar V, Arno M, Preux L, Millar V, Page C, Collins H, Mudway I, Dailey LA, Forbes B. In Vitro Multiparameter Assay Development Strategy toward Differentiating Macrophage Responses to Inhaled Medicines. Mol Pharm. 2015 Aug 3;12(8):2675-87. doi: 10.1021/acs.molpharmaceut.5b00048. Epub 2015 May 19. PubMed PMID: 25941945.

Brown CC, Esterhazy D, Sarde A, London M, Pullabhatla V, Osma-Garcia I, Al-Bader R, Ortiz C, Elgueta R, Arno M, de Rinaldis E, Mucida D, Lord GM, Noelle RJ. Retinoic acid is essential for Th1 cell lineage stability and prevents transition to a Th17 cell program. Immunity. 2015 Mar 17;42(3):499-511. doi: 10.1016/j.immuni.2015.02.003. Epub 2015 Mar 10. PubMed PMID: 25769610; PubMed Central PMCID: PMC4372260.

2014

Brough HA, Cousins DJ, Munteanu A, Wong YF, Sudra A, Makinson K, Stephens AC, Arno M, Ciortuz L, Lack G, Turcanu V. IL-9 is a key component of memory TH cell peanut-specific responses from children with peanut allergy. J Allergy Clin Immunol. 2014 Dec;134(6):1329-1338.e10. doi: 10.1016/j.jaci.2014.06.032. Epub 2014 Aug 10. PubMed PMID: 25112699.

Petrova A, Celli A, Jacquet L, Dafou D, Crumrine D, Hupe M, Arno M, Hobbs C, Cvoro A, Karagiannis P, Devito L, Sun R, Adame LC, Vaughan R, McGrath JA, Mauro TM, Ilic D. 3D In vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells. Stem Cell Reports. 2014 Apr 24;2(5):675-89. doi: 10.1016/j.stemcr.2014.03.009. eCollection 2014 May 6. PubMed PMID: 24936454; PubMed Central PMCID: PMC4050479.

Moyes DL, Shen C, Murciano C, Runglall M, Richardson JP, Arno M, Aldecoa-Otalora E, Naglik JR. Protection against epithelial damage during Candida albicans infection is mediated by PI3K/Akt and mammalian target of rapamycin signaling. J Infect Dis. 2014 Jun 1;209(11):1816-26. doi: 10.1093/infdis/jit824. Epub 2013 Dec 19. PubMed PMID: 24357630; PubMed Central PMCID: PMC4017362.

 

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