Biological markers, or Biomarkers, are molecules found in body tissues or fluids which indicate normal or aberrant processes, disease conditions or responses to therapeutic drug treatments.
The Facility has a proven track record in this type of protein profiling work, involving both qualitative and relative quantitative comparisons between control and disease samples in biological matrices. In particular, we have expertise in analysing plasma, serum and cerebral spinal fluid but we can analyse proteins and peptides from any complex biological sample.
We have discovered many biomarkers of interest using the techniques we can provide. Once a biomarker of interest has been discovered, we have the capabilities to take it to the further stages of absolute quantitation with labeled peptides and selective reaction monitoring assay development.