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Projects and publications

Projects


Major Projects 

 

PROJECT

 

 

MAIN INVESTIGATOR/

RESEARCH GROUP

 

 

TECHNIQUE

 

 

Molecular Mass determination/Accurate mass measurement

 

 

 

KCL Staff

 

 

Exactive (LC-HRMS), LTQ DECA XP (ESI), MALDI

 

Characterisation of phase 1 metabolites of new psychoactive active substances produced by human liver microsomes

 

 

Drug Control Centre, KCL

 

 

LCMS, LC-HRMS

 

Investigation of glycan derivatisation for enhancing detection by liquid chromatography tandem mass spectrometry

 

 

Drug Control Centre, KCL

 

LCMS, LC-HRMS

 

Measurement of Betaine and N,N-Dimethylglycine in liver samples

 

 

Cardiovascular Division, James Black Centre, Denmark Hill, KCL

 

 

LC-MS

 

Measurement of hydrogen sulphide and homo-cysteine in plasma and tissue samples

 

Cardiovascular Division, James Black Centre, Denmark Hill, KCL

 

 

LCMS, LC-HRMS

 

Investigation of global DNA Methylation and Hydroxymethylation

 

Dept. of Forensic Science and Drug Monitoring, KCL

 

 

LC-MS

 

Measurement of amino acids in cell samples

 

Cardiovascular Division, James Black Centre, Denmark Hill, KCL

 

 

LC-MS

 

Detection of 3-NBA DNA adducts

 

Environmental Carcinogenesis Group, Analytical and Environmental Sciences Division, KCL

 

 

LCMS

 

Mass spectrometric analysis of albumen peptides for carcinogen adducts

 

Genetic and Environmental Toxicology Group, Analytical and Environmental Sciences Division, KCL

 

 

LCMS, LC-HRMS

 

Determination of dapivirine, darunavir, and other antivinol druge,  in serum and vaginal fluids and tissue samples.

 

Oral Immunology, Hodgkin Building, Guy’s Campus SE1 1UL, KCL

Pharmaceutical Science, KCL

 

 

LCMS

 

Semi-targeted screening of pharmaceuticals and related contaminants in river Thames

 

Dept. of Forensic Science and Drug Monitoring, KCL

 

 

LC-HRMS

 

Investigation of pharmaceuticals and personal care products from aquatic invertebrates, gammarus pulex

 

 

Dept. of Forensic Science and Drug Monitoring, KCL

 

LCMS

 

Investigation of  the individual mononucleotides modifications, i.e. AMP, CMP, GMP, TMP

 

 

British Heart Foundation Centre of Excellence, KCL

 

LCMS

 

Determination of bisphenol A and bisphenol A glucuronide in serum

 

 

Analytical and Environmental Science Division, KCL

 

 

LCMS

 

Determination of Fe in proteins

 

 

Pharmaceutical Sciences, KCL

 

 

ICPMS

 

Determination of metals in roadside air filters/urine

 

Lung Biology, ERG, Analytical and Environmental Science Division, KCL

 

 

ICPMS

 

Determination of metals in roadside air filters

 

ERG, Analytical and Environmental Science Division, KCL

 

 

ICPMS

 

Metabolic profiling in serum from the critically ill patients

 

Guy' & St Thomas' NHS Foundation Trust, Department of Critical Care Medicine, NHS

 

 

LCMS, LC-HRMS and GCMS

 

Stability and purity study of Vaper Peptides Vaccine

 

Foundation Trust and KCL, Dept. of Haematological Medicine, The Rayne Institute, Denmark Hill, KCL

 

 

LCMS

 

Determination of beclometasone dipropionate (BDP) and beclometasone-17-monopropionate (17-BMP)

 

 

Institute of Pharmaceutical Science,KCL

 

LCMS

 

Investigation of heart and perfusate metabolic profiling

 

Cardiovascular Division, The James Black Centre, KCL

 

 

LCMS, LC-HRMS and GCMS

 

Investigation of Vitamin D and it’s metabolites in human skin.

 

 

Chemical Biology, IPS, KCL

 

LCMS

 

Determination of twelve flavonoids in human urine.

 

Diabetes & Nutritional Sciences Division

 

 

LCMS

 

Investigation of 2-methyl-norharmanium ion (2-MeNH) production.- ion (2-MeNH

 

 

Chemical BiologyIPS, KCL

 

 

Investigation of short chain fatty acids in rat faeces

 

Division Diabetes and Nutritional Sciences, KCL

 

 

GCMS

 

Investigation of AcMT impurities.

 

University of Aberdeen

 

 

LCMS

 

Investigation effect of chlorinated products on human dentine.

 

 

Clinical Dentistry, Dental Institute, KCL

 

 

GCMS

 

Determination of Dipyridamole in rat plasma

 

 

School of Pharmacy, UCL

 

LCMS

 

 

Gd uptake studies

 

Imaging Sciences, KCL

 

 

ICPMS

 

 

Determination of Trace Metals in Drugs

 

 

University of Aberdeen

 

ICPMS

 

Distribution of nanodots in rat organs

 

 

UCL

 

ICPMS

 

Development of new formulation of the anti-cancer drug – quantification of the anti-cancer drug and it’s metabolite in plasma and tissue

 

 

Department of Pharmaceutics, UCL School of Pharmacy

 

LCMS

 

PGP and AcPGP in serum

 

 

Imperial College

 

 

LCMS

 

Determination of Ca, Na & Mg in Saliva

 

 

Saliva research group, Guys Dental Hospital, KCL

 

 

ICPMS

 

Determination of Zn in proteins

 

 

Nutrition, KCL

 

ICPMS

 

 

Investigation of elements in plasma for different dietary groups

 

Lipidomics & Nutrition Research Centre, London Metropolitan University

 

 

ICPMS


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