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UK-Israel Synergy Symposium

Protein misfolding in ageing and neurodegeneration: from basic biology to drug development

Venue: Room 1.67 Franklin Wilkins Building, Stamford Street, London, SE1 9NH 

26th - 28th March 2018

This symposium will bring together top UK and Israeli scientists working in different fields of Neuroscience, related to ageing diseases and neurodegeneration, sharing new ideas and latest results to develop complementary ways of thinking. Specific areas of interests will be the importance of post-translational modifications in protein aggregation, cross-talk between ageing diseases, the frontiers of dementia studies and the development of new approaches to drug design. The event will provide an important occasion for confrontation, and a reference forum to promote new collaborations. The personal face-to-face interactions created during this meeting will be essential for increasing scientific communication and establishing new long-lasting collaborations. Our goal is not only to learn more about cutting-edge research on protein aggregation in neurodegeneration, but also to create a marketplace of ideas and tools for a more global approach to neuroscience.



  • 26th March 2018  - opens from 1pm (13:00-17:00)

  • 27th March 2018  - all day (09:00- 17:00)

  • 28th March 2018  - closes 12pm (09:00-12:00)

Conference Programme

Symposium topics


The meeting will include the following potential topics of discussion:


  • The mechanisms of neurodegenerationin aging, which will focus on the mechanism that trigger protein misfolding during aging;

  • Molecular chaperons in ageing-related neurodegeneration, which will focus on protein folding-assisted processes, what can cause their failure and what would be the consequences;

  • The cross-talk between different aging diseases, where the relationship between the mechanisms that triggers aging diseases will be discusses;

  • Molecular mechanisms of unfolding and aggregation, which will bring the attention towards the intra- and inter-molecular interactions that lead to conformational rearrangements in proteins;

  • The role of post-translational modifications in aggregation, in which the role of phosphorylation, glycation, glycosylation, ubiquitination and other epigenetic events will be discussed;

  • Drug design and therapeutics perspectives, which will give us the chance to discuss drug development oriented towards therapeutics.

  • Prion-like behaviour in ageing diseases, which will help a better understand how prions cause tissue damage leading to further aggregation and neurodegeneration; 





The meeting will be open to scientists from students to professorial level.

The attendance fee is £200 for senior scientists and postdocs, and £150 for students. This includes all talks, four tea & coffee breaks, lunch on the second day of the symposium, and programme and badge.

There is fee reduction of 50% for early registration and presentation of a poster.

To register, please follow this link

A maximum of 60 people will be accepted to allow a good but limited mixture of people.

During the three days, an “Offers and Requests” poster will be made available to everyone who wants to offer expertise or look for collaborations.

A poster session will be organised at this event.

You are encouraged to
submit a poster (size A1) to the email address  by 10/3/2018. The best poster will be awarded with a prize.

Directions to hotel and conference venue


  • Annalisa Pastore (King’s College London)
  • Daniel Segal (Tel Aviv University)
  • Elsa Zacco (King’s College London)

For queries about this event please contact


 British Council 

King's College London

British Council



Frontiers logo (002)

Uk Science and Innovation Network

 UK ScienceInnovation Network (002)

 King's College London

Ageing Research at KCL

ageing research at KCL


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