Clinical Trials: Design - Conduct and Analysis
Date: 8th April – 12th April 2019
Venue: Seminar Rooms 1 & 2, Main Building, Institute of Psychiatry, Psychology & Neurosciences (IoPPN), King's College London. View Map.
The course provides a comprehensive introduction to trial design features used to mitigate bias, important aspects of trial design, conduct, analysis and reporting, and challenges and solutions for conducting RCTs with some focus on behavioural interventions.
Throughout the course the emphasis will be on practical issues faced by researchers in the conduct of RCTs in mental health, and participants will be provided with skills to design and conduct rigorous RCTs in this research area.
This course requires an application to be made see more information tab on how to apply. Some practical sessions will involve the analyses and interpretation using practice data sets. STATA syntax/SPSS instructions/R code will be provided and explained, but some familiarity especially with Stata/SPSS software is advised.
Successful participants will need to bring their own laptop computer with working installations of: 1) Stata version 14 or higher or SPSS, 2) the R program to the course.
Subject Specific: Knowledge, Understanding and Skills
On successful completion of this course the student should be able to:
- Understand the key sources of bias within epidemiology study designs
- Understand the fundamental features within clinical trial within a mental health framework
- Participants will also critically appraise published trials.
General: Knowledge, Understanding and Skills
On successful completion of this module the student should be able to:
- Communicate ideas effectively and professionally by written, oral and visual means
- Interact effectively in a group
- Implement suitable designs for different settings in responding to a commissioned funding call;
- Practical skill to develop a database framework, and codebook; trial protocol (as well as other essential documentation);
- Interpretation and dissemination of clinical trial findings using Stata or SPSS.
Cost and Booking
Booking / Application
- External Early bird: £855 (till 18/10/18, price thereafter £950)
- KCL Staff Early bird: £641.25 (till 18/10/18, price thereafter £712.5)
- KCL Student Early bird: £427.5 (till 18/10/18, price thereafter £475)
- Other student Early bird: £641.25 (till 18/10/18, price thereafter £712.5)
- King's Health Partners Early bird: £641.25 (till 18/10/18, price thereafter £712.5)
That is, 50% discount to King's College London PhD students, 25% discount to other students and staff at King's College London and King's Health Partners.
Booking for this course has now closed.
To apply please email email@example.com with the following details:
Subject: Application for Clinical Trials: Design - Conduct and Analysis 2019
Contact Phone Number:
- Are you affiliated with KCL and/or King's Health Partners?
- If Yes, indicate how you are affiliated with KCL and/or King's Health Partners
- Indicate your education/employee status: KCL PhD, KCL student, KCL staff, King's Health Partners affiliate, External Student or External
- In 100 words, state why you wish to enrol/participate in this course:
In 100 words, state which skills you hope to acquire:
Once your application has been approved, you will be sent a link to payment and a discount code if one is to be applied.
Dr Kimberley Goldsmith (Academic Lead)
Dr Ben Carter (Academic Lead)
Kimberley is a Biostatistician and Clinical Trials specialist with an interest in complex psychological therapy treatments.
She holds an Honours degree in Biology and MSc in Microbiology and Virology from McMaster University, as well as a Master of Public Health from Oregon Health & Science University. She was awarded a NIHR Doctoral Research Fellowship and graduated with a PhD in Biostatistics from King’s College London. She was subsequently appointed as a BRC Lecturer in Clinical Trials post in the Department of Biostatistics & Health Informatics, followed by an appointment to Senior Lecturer in Medical Statistics in 2015.
Research interests and PhD supervision
Kimberley has extensive experience in clinical trials in mental health and other fields, encompassing the conduct, analysis and dissemination of several single and multi-centre clinical trials.
Her particular interest is in the study of treatment mechanisms of psychological therapies/mediation analysis, including the novel application of longitudinal structural equation models to study mediation of treatment effects. To date this work has led to a greater understanding of therapeutic mechanisms and refinement of the treatments. It is also widely applicable to the study of treatments in other disease areas and public health interventions. Kimberley is also interested in structural equation, latent variable and longitudinal modelling more generally.
She sits on the BRC Executive Committees at the Institute, where she enjoys contributing to wider research strategy, and is an active MSc, PhD and DClin Psych supervisor.
See Kim's research portal here.
Professor James Wason, Newcastle University (Academic Lead)
Ben is a Senior Lecturer in Biostatistics. Ben's previous roles have been Senior Lecturer in Medical Statistics (Honorary, Cardiff University) and Associate Professor of Medical Statistics (Honorary, The University of Nottingham).
Ben's methodological interests include:
- Methods in meta-analysis, including: network meta-analysis; individual participant meta-analysis; and meta-analysis of non-randomised designs
- Measurements using mHeath data.
- The design and analysis of cluster Randomised Controlled Trials.
- My broader research interests include:
- The influence of eHealth on our lives.
- The impact of screen-based devices on our sleep; better usage management.
- Evidence-based eHealth.
- Improving health for mental illness patients.
- Public health. Including preventing decline in physical and mental health.
See Ben's research portal here.
I am a statistician with interests in methods for improving the design and analysis of clinical trials. As well as working in methodology development I have a great interest in collaborating on real trials to apply new methods in practice.
I have been in Newcastle since July 2017. I currently retain a part-time position in the MRC Biostatistics Unit, University of Cambridge.
I am part of the IHS Biostatistics Research Group.
Areas of expertise
- Clinical trials
- Novel trial design
See James' research portal here.
Your place will not be confirmed until payment has been made. Failure to cancel without sufficient notice will forfeit your course fee and access to future courses. If you would like to pay by internal transfer, please contact firstname.lastname@example.org