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Paradigm Development

Paradigm Development

The Paradigm Development Team comprises of Jeff Dalton, Dave Gasston and Chris Andrew.

Introduction

The team’s remit is to design and provide the best possible resources for successful functional MRI study within the CNS. This necessitates the continued redesign and update of both the infrastructure and software.
Over the past 16 years, we have implemented hundreds of fMRI paradigms. Some have been in association with other prestigious Universities, either national or international, and some with the pharmacological industry.

Practicalities

In practical terms the study Principal Investigator will initially decide, with some consultation, which kind of paradigm they wish to run dependent upon the subject group, the condition being investigated and with regard to past experience or publications.

Once the protocol has been decided the investigators will meet with the team to best decide how to implement a paradigm, or batch of paradigms, to run within the CNS MRI scanners. 

The main success of any functional imaging study is the requirement for a properly designed paradigm. The paradigm programs are written in house in order to provide the most flexible arrangement. Additional input may be provided in the form of consulting on the design or purchase of specialised equipment for any particular study. Discussions may be appropriate to decide on the best method of obtaining a response from a subject within the scanner environment. It is becoming increasingly common to incorporate the monitoring of physiological variables such as heart rate and respiration during a study. This will be incorporated into the paradigm during the set up of any particular study if required.

 

 

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