Take part in our research
We currently have the following studies you can take part in. Please see the inclusion and exclusion criteria for each trial before contacting us.
Computerised Training for Bulimia Nervosa and Binge Eating Disorder
The purpose of the research is to explore the feasibility of a phone app in targeting binge-eating episodes, and to explore mechanisms that might be involved in this behavioural change. It will do so by exploring the added benefit of the app over treatment as usual.
Once you get in touch with Rayane Chami (email@example.com), you will receive an information sheet with the study details. If you are still interested in taking part, a researcher from the team will get in touch with you to ensure the study would be safe and suitable to you. After this, you will receive a consent form and a link to the first battery of questionnaire (~25 minutes to complete).
After completing the questionnaire, you will be randomised to either the treatment as usual condition or the treatment as usual + training condition.
-If you are allocated to the treatment as usual group, the researcher will set up a quick phone call with you to let you know.
-If you are allocated to the treatment as usual + training group, you may choose to meet the researcher via Skype or in person at King’s College London in Denmark Hill for 20-30 minutes to go through the training together and ask any questions relating to it. You will then be asked to complete a 3-min daily food diary and an 8-minute game on your computer ideally every day for 4 weeks.
After the 4 weeks, you will receive a second battery of questionnaires (regardless of the group you are randomly allocated to; ~20 minutes to complete). Eight weeks after the start of the study, you will receive a follow-up questionnaire (~20 minutes to complete). If you had been allocated to the treatment as usual group, you may choose to receive the training once you have completed the follow-up questionnaire.
Who can take part?
The inclusion criteria include:
- Age 18-60
- Diagnosis of bulimia nervosa or binge eating disorder OR reason to believe one may meet criteria for diagnosis
- Currently receiving treatment (including therapy and/or medication)
- BMI above 18.5
- Fluency in English
- No visual impairment that cannot be repaired with eyeglasses or contact lenses.
- No ‘severe’ psychiatric comorbidity (e.g. psychosis).
- No alcohol/drug abuse
You will receive a £15-pound bank transfer once you complete the post-intervention questionnaire.
How can someone take part?
The first step is to get in touch with Rayane Chami on Rayane.firstname.lastname@example.org to express interest. After this, Rayane will introduce herself and send the information sheet with more details. If the individual expresses interest in taking part, a 15-minute phone screening will be set up to assess safety and suitability.
The ENTER Study
CytAN: Cytokines in individuals with a diagnosis of anorexia nervosa
The ENTER study: Effects of Neuromodulation and cognitive training on eating responses.
We are investigating a novel way of preventing weight gain in people taking antipsychotic medication. The intervention involves engaging in a simple computer-based training that aims to change the automatic responses towards food, while receiving a safe brain stimulation procedure that is widely used in research.
Pre- and post-treatment assessments using questionnaires and food related tasks, together with 5 sessions of computer-based training combined with non-invasive brain stimulation (not more than an hour a day for 5 days).
- Male and female adults
- Aged between 18 and 65 years
- DSM-V diagnosis of schizophrenia or schizoaffective disorder
- On a stable dose of antipsychotic medication for the past 6 weeks
- Individuals with a significant /unstable medical or psychiatric disorder other than schizophrenia or schizoaffective disorder (e.g. substance dependence)
- Individuals taking antidepressant medication who have not been on a stable dose for at least 6 weeks
- Individuals with allergies to any of the foods presented in the study
- Individuals who cannot understand verbal English or written information in English
- Individuals who do not want or are not able to provide informed consent
- Individuals with a history of epileptic seizures, stroke or brain injury
- Individuals who have any implanted metal devices in the head
- Individuals with frequent or severe headaches or dizziness
- Individuals who are pregnant
- A tDCS safety questionnaire will also be administered and if considered not safe to deliver tDCS, individuals will subsequently be excluded on this basis.
You will be reimbursed £90 for your participation.
For further information, please contact:
Tel: 0207 878 5608.
This project aims to understand the role of the immune system, specifically cytokines, in anorexia nervosa. Our brain and behaviour are influenced by the immune system. Cytokines are important messenger molecules in the immune system. There are many different types of cytokines with different roles. They can be measured in the blood and can tell us a lot about inflammation in the body. Research has shown that individuals with a diagnosis of anorexia nervosa tend to have elevated levels of certain cytokines in their blood. However, very few cytokines have been measured and there are a number of cytokines that are important for the immune system and the brain that have never been measured in individuals with a diagnosis of anorexia nervosa. Also, we do not know whether cytokine levels are different in individuals with a diagnosis of anorexia nervosa who have different clinical characteristics. These include factors such as illness duration, eating disorder symptom severity, and severity of co-existing disorders (e.g. depression).
In this study, we want to measure a large range of cytokines to find out if the level of cytokines differs between healthy control participants and individuals with a diagnosis of anorexia nervosa. We also want to investigate whether cytokine levels are related to certain clinical characteristics. This study will help us to understand if cytokines are involved in the underlying biology of anorexia nervosa. As there are medications available to influence cytokine production, cytokine levels and cytokine effects, our research may lead to the development of future treatments to help with anorexia nervosa.
Once you have read and understood the information sheet you will have a brief phone call with a researcher to check your eligibility. If you are eligible you will arrange a 1.5-hour research session at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London (London, SE5 8AF). In this session, you will complete a short questionnaire pack, have your height, weight and body composition measured, and you will provide blood samples. All data will be kept anonymous.
Who can take part?
Inclusion criteria - You are eligible to take part if you:
Anorexia Nervosa participants:
- Are a female aged 18 or older
- Have a current diagnosis of Anorexia Nervosa
- Have a body mass index (BMI) less than 18.5kg/m2
- Are fluent in English
Recovered Anorexia Nervosa participants:
- Are a female aged 18 or older
- Had a diagnosis of Anorexia Nervosa in the past
- Have a body mass index (BMI) more than 18.5kg/m2 for at least 6 months
- Have restored menstruation
- Have not binged, purged or engaged in significant restrictive eating patterns
- Are fluent in English
- Are a female aged 18 or older
- No current or past psychiatric diagnosis
- Have a body mass index (BMI) more than 18.5kg/m2
- Are fluent in English
Exclusion criteria - You are not eligible to take part if you:
- Have current acute or chronic inflammatory conditions (e.g. asthma, Crohn’s disease, arthritis, psoriasis, inflammatory bowel disease)
- Are pregnant
You will be reimbursed £15 for your time and effort.
How can you take part?
If you are interested in taking part, or would like more information, you can contact Olivia or Bethan at:
Email: email@example.com Phone: 0207 848 5977
Email: firstname.lastname@example.org Phone: 0207 848 0183
ICARUS - Investigating Concurrent Cognitive Bias Modification Training and Transcranial Direct Current Stimulation in Binge Eating Disorder
FLARe in AN: Fear Learning in Anorexia Nervosa
Cognitive training programmes and non-invasive brain stimulation techniques have each shown promise in research trials that treat symptoms of eating disorders. This study aims to investigate the feasibility of combining approach bias modification training (ABM) and transcranial direct current stimulation (tDCS) to treat binge eating disorder. It will evaluate if concurrent sessions of [ABM + real tDCS] are superior to [ABM + sham tDCS] and the wait-list control group in terms of reducing symptoms of binge eating disorder such as frequency of objective binge eating episodes and food cravings.
Participation consists of;
- Completion of 3 assessment sessions across 7 weeks
- After the baseline assessment, participants will be randomly allocated to one of three study conditions
- Participants assigned to one of the two intervention conditions will be asked to attend 6 sessions where they will perform the ABM task while receiving either real or placebo tDCS, in addition to completing the post-treatment and follow-up assessments. This brain stimulation technique is widely used and considered safe.
- Participants assigned to the control group will not receive any intervention, and will be asked to attend the post-treatment and follow-up assessments.
- Participants in the control group will be offered the opportunity to receive [ABM + real tDCS] after the follow-up assessment at 7 weeks
How long does it take?
- All participants in both the intervention and control groups of the study will complete 3 assessment sessions across 7 weeks, comprised of an in-person visit (between 60-150 minutes) and online questionnaires to complete at home (30 minutes).
- Participants in the intervention groups will attend 6 sessions of combined cognitive training and tDCS across 3 weeks, lasting 40-50 minutes per session.
Where will the study take place?
All parts of this study will be conducted in the KCL Institute of Psychiatry, Psychology and Neuroscience in Denmark Hill, except for the initial study screening over the phone.
• Male and female community-dwelling adults
• Aged between 18 and 70
• Symptoms of Binge Eating Disorder (not Bulimia Nervosa)
• BMI greater than 24.9 kg/m²
- Individuals with a significant/unstable medical or psychiatric disorders needing acute treatment in its own right (e.g., substance dependence, acute suicidality)
- Individuals taking antidepressant medication who have not been on a stable dose for at least 2 weeks
- Individuals with a history of epileptic seizures, stroke, or brain injury, who have any implanted metal devices in the head, frequent or severe headaches or dizziness
- Individuals who smoke >10 cigarettes per day
- Individuals who drink >3-4 units (men) or 2-3 units (women) of alcohol per day
Additional excluding criteria may apply and inclusion will be determined by the study screening.
All participants are reimbursed £60 for completing the 3 assessments, and travel expenses for the 6 intervention sessions will be covered up to £10 per visit.
For further information, please contact: email@example.com
We want to recruit both
a) individuals currently living with AN, and
b) individuals now weight-restored who previously lived with AN.
This study aims to examine how easily people become fearful or worried about things they encounter in daily life, and how long this anxiety lasts for.
The whole study takes place online through your mobile phone, so you don't need to travel anywhere. All you need to do is download an app and it will guide you through the entire process. You decide where and when you want to complete the study – as long as it is a quiet room so that you can concentrate without distraction. You will be able to contact the researcher coordinating the study at any time during your participation, should you have any questions or encounter any issues.
First, you will be asked to complete some questionnaires. Following completion of the questionnaires, you will be shown pictures of geometrical shapes on top of a picture background. Some pictures will be accompanied by a loud noise (a scream). Your task is to rate your expectation of hearing the noise when you see different shapes.
The study involves two sessions. The first session will take approximately one hour. The second session needs to be completed the day after and will take around 10 minutes. We will reimburse you with a £10 voucher for your time on completion of the study.
If you are interested in taking part or have any questions, please email me on firstname.lastname@example.org
The FOCUS Study
Transition Care in Anorexia Nervosa Through Guidance Online from Peer and Carer Expertise (TRIANGLE)
The FOCUS Study: A randomised controlled feasibility study of food related computerised attention training for obesity versus active (mindfulness-based intervention (MBI) and waiting list control.
This study is designed to compare the effects on treatment outcomes of two different attention trainings in people who are overweight or have obesity.
We hope to determine which attention training has greater effects on treatment outcomes such as food craving and related difficulties such as anxiety. We also hope to explore underlying mechanisms that contribute to these improvements. This will help us to determine if and which training should in future become part of usual clinical care for people with eating and weight disorders.
During a baseline assessment, participants will be asked to complete a set of questionnaires and computer and behavioural tasks. After this initial state, participants will be assigned to an attention training or to a waiting list condition. The trainings consists of eight weekly sessions in our lab, and daily short trainings at home. The Lab sessions will last for about 30 minutes and the home trainings are 10 min long. For your home sessions, we will provide you with an electronic tablet at the beginning of the study to complete the trainings and will kindly ask you to return it at the end of the eight weeks.
At the end of the training sessions (on week eight), participants will undergo a similar assessment to the one at the beginning of the trainings. Lastly, four weeks after having completed the training, participants will be contacted for a brief follow-up assessment that can be completed online (e.g. at home).
You are eligible to take part if you are:
- Male or female
- 18 years old or older
- overweight or have obesity
You are not eligible to take part if you:
- Have a past or present diagnosis of Anorexia Nervosa, Bulimia Nervosa or Eating disorder not otherwise specified (EDNOS).
- Are on a dose of any psychoactive medication that has not been stable for at least 14 days prior to participation in the study
- Are taking medication for weight loss
- Have been diagnosed with Diabetes Mellitus
- Are pregnant (either currently or during the past 6 months)
- Experiencing a major psychiatric disorder (e.g. major depressive disorder, substance dependence, schizophrenia or bipolar disorder) needing treatment in its own right
- Have a regular current or past mindfulness meditation or yoga practice (defined as > 20 minutes, twice or more times per week during the past 2 months)
- Have any visual impairments that cannot be corrected with contact lenses or glasses
You will be compensated with £50 for your time and efforts of participating upon successful completion of all parts of this study and the follow-up assessment.
Social information processing in adolescents with eating disorders
TRIANGLE is a national research study involving 28 hospital sites in the UK. The study investigates the journeys of adults with anorexia nervosa admitted to intensive hospital care for anorexia nervosa and their carers (family members, friends). The study is also designed to examine how the transition period from hospital to home can be improved. This period can be particularly challenging for everyone involved. We have developed a website with materials built for and by patients and carers who have experienced this problem and want to help others.
The main aims of the TRIANGLE study are to:
- Track the journeys of patients with anorexia nervosa admitted to hospital and their carers over an 18 month period
- Examine whether some patients and their carers (chosen at random) may benefit long-term from extra resources and support delivered online, during the transition from hospital to home
Once you have read and understood the information sheet you will have a brief phone call with a researcher to check your eligibility. If you are eligible you will be asked to complete a consent form and an initial questionnaire on the study website. Once you complete the initial questionnaire, your involvement in the project will last 18 months. A chance-related system will determine your study group allocation and you will be asked to complete some follow-up online questionnaires throughout the 18 months at key time points (3, 6, 9, 12, 18 months). You will receive access to a self-monitoring tool and depending on which group you are allocated to you will also receive access to some online resources whilst still receiving support from your clinical team. At the end of the study all participants will have access to the study materials, and you will be reimbursed up to £60 for completing the questionnaires.
Who can take part?
PATIENT IS ELIGIBLE IF:
- Aged 16+
- Anorexia Nervosa (DSM-V, including subclinical/atypical)
- Receiving inpatient or day care (min. 3 days/week)
- OR recently discharged (within 4 weeks)
- Access to internet
- Willing to ask carer to join study too (family/friend)
PATIENT IS NOT ELIGIBLE IF:
- Insufficient English
- Severe mental/chronic physical illness needing specialist treatment (e.g. Cystic Fibrosis, Psychosis, Diabetes Mellitus)
- Previously received “ECHOMANTRA” materials (as part of treatment or a research trial)
You and your carer will be reimbursed up to £60 for your time and efforts.
How can you take part?
If you are interested in taking part, or would like more information, you can contact Katie or Dan at:
Email: email@example.com Phone: 0207 848 5980
Email: firstname.lastname@example.org Phone: 0207 848 5963
This project aims to understand more about social interactions and relationships among young people with eating disorders compared to those without eating disorders.
Once you have understood the information sheet the researcher will arrange a brief telephone screening with you to confirm your eligibility to take part. If you are eligible to participate you will be invited to the research lab in 103 Denmark Hill, to complete a series of questionnaires about eating, mood and anxiety and some tasks related to social interactions and social networks. The researcher will ask if they can measure your weight and height during the experiment, but you can choose to be blind weighed if you prefer. The study will take two hours and you will receive a £15 Love To Shop voucher for your time and efforts.
Inclusion criteria: -
- Males or females
- Aged between 13-17
- Fluent in English
- Have anorexia nervosa or bulimia nervosa (or subclinical/atypical)
- Or no history of mental health conditions
Exclusion criteria: -
- Neurological impairments
- Severe medical / psychiatric comorbidity (e.g. psychosis)
You will be reimbursed with a £15 ‘Love To Shop’ voucher for your time and efforts.
How can you take part?
If you are interested in taking part or would like more information, please contact Katie:
Phone: 0207 848 5980