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Take part in our research

Take part in our research

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We currently have the following studies you can take part in. Please see the inclusion and exclusion criteria for each trial before contacting us.

PLUS Study - Personality and Living of University Students

 PLUS Logo

Starting university can be a fun and exciting time, but also stressful and demanding. This study will look at whether a specially-designed online programme can improve student wellbeing.

Taking part involves filling out online questionnaires and completing a series of online sessions. You’ll receive feedback on your questionnaire responses, and each time you complete a set on online questionnaires you’ll be entered into a raffle for an iPad.

 

Aims:

The PLUS study aims to investigate whether an online programme designed to help first-year uni students can improve wellbeing. 

 

What’s involved?

Participants are asked to complete a set of online questionnaires covering topics such as personality, mental health and health-related behaviours (e.g. alcohol consumption). After this, participants receive personalised feedback on their responses, and are given access to a series of online modules designed to support students during their first year at university. They are asked to work through these modules within a three-month period, and to fill out questionnaires four times over a 12-month period.

 

What’s in it for participants?

The online sessions are designed to help and support first-year students, and we hope participants will find the content useful and interesting. Participants also get feedback on their questionnaire responses, allowing them to learn more about themselves, their personality and their strengths and weaknesses. Finally, each time participants complete one of the online assessments, they’ll be entered into a raffle for an iPad.

 

Where will the study take place?

All parts of this study will be conducted online.

Inclusion Criteria

  • Undergraduate and postgraduate students studying at a UK university.

Exclusion Criteria

  • Received psychological therapy or a psychiatric diagnosis in the past 12 months
  • Ever received a diagnosis of psychosis or bipolar disorder.

 

Contact

If you are interested in participating or would like further information, please contact Madeleine Irish (madeleine.irish@kcl.ac.uk) or visit our project website (https://www.icare-online.eu/en/Plus.html)

 

Funding

The project is part of ICare, a European-wide research project funded by the European Commission, which aims to implement internet-based interventions that prevent mental health problems in different settings across Europe https://www.icare-online.eu/en/icare.html

                 EU Commission Logo

everyBody Plus - Online treatment and support for bulimia and binge
eating disorder

ICARE LogoPeople with bulimia nervosa or binge eating disorder often wait a long time for effective treatment. We are trying to bridge this gap by providing people with different types of online                                                                              treatment/support.

Participants either receive everyBody Plus, an 8-session internet-based, guided self-help programme, based on cognitive behavioural therapy, or alternatively they receive regular online symptom monitoring. Participants in both the everyBody Plus and symptom-monitoring group will have access to visual feedback charts on the progress of their symptoms diary, and all participants will complete 4 assessment questionnaires online.

 

Aims:

To conduct a randomised controlled trial (RCT) of the everyBody Plus online intervention compared to online symptom monitoring, in a sample of 138 females in the United Kingdom. This study aims to investigate whether everyBody Plus reduces the time until a person achieves a clinically relevant improvement in their eating disorder symptoms after face-to-face treatment, compared to receiving online symptom monitoring. Symptom monitoring is known to have a beneficial effect on eating disorder symptoms.

 

What’s involved?

  • 15 minute phone call screening with study researcher
  • Self-enrolment on study website
  • Enter frequency of eating disorder symptoms once a week for 12 months
  • Complete 4 online questionnaire assessment sessions over 12 months
  • Participants who are randomly assigned to the intervention condition will additionally have access to the online modules; 8 weekly sessions for 8 consecutive weeks, which will take approximately 60 minutes each. This involves writing journal entries and posting thoughts/questions on the online discussion forum. Once a week, you will receive personalised email feedback from a trained moderator.

 

What’s in it for participants?

All participants across both conditions of the study will be awarded points for each completed weekly symptom logging and 4 questionnaire assessments over 12 months. Participants can earn a maximum number of 92 points (€92), which will be converted into pounds and paid upon completion of the study. 

 

Where will the study take place?

All parts of this study will be conducted online, except for the initial study screening over the phone with a researcher from King’s College London

 

Inclusion Criteria

You may be eligible to take part if you have/are:

  • Female
  • Aged 18 or over with symptoms of/a diagnosis of bulimia, binge eating disorder or another eating disorder with binge eating

 

Exclusion Criteria

You are not eligible to take part if you have/are:

  • Male
  • Under the age of 18
  • A body mass index lower than 18.5kg/m2

Your eligibility will be fully determined after a phone call screening questionnaire.

 

Contact

If you are interested in participating or would like further information, please contact Vanessa Yim (vanessa.yim@kcl.ac.uk). An overview of the study can also be found on our project website (https://www.icare-online.eu/en/everybody-plus.html).

Please note that contacting us for further information or partaking in the phone call screening does not mean you are obliged to take part in the study.

 

Funding

The project is part of ICare, a European-wide research project funded by the European Commission, which aims to implement internet-based interventions that prevent mental health problems in different settings across Europe https://www.icare-online.eu/en/icare.html  

EU Commission Logo

We Can Study - web-based intervention for carers of individuals with anorexia nervosa


ICARE LogoWe Can – A randomised controlled trial of a web-based intervention for carers of individuals with anorexia nervosa

Carers of people with anorexia nervosa play an important role in recovery, but often feel ill equipped to effectively support their loved one. This can have a negative impact on both the person with anorexia, and the mental health of their carer. We have developed and evaluated We Can, a web-based skills training programme, designed to support carers of people with anorexia.

 

Aims

This study aims to investigate the effectiveness of a web-based skills package (‘We Can’) to support carers of individuals with anorexia nervosa, and to look at how different levels of support within the intervention may affect the results. We are interested in how the We Can skills package affects both the carer using the package, and also the person with anorexia whom they care for.

 

What’s involved?

Carers of adults with anorexia will be able to participate in an online skills programme, which they can access anywhere with an internet connection. Participation consists of;

  • Completion of 8 online interactive modules over a 12-week period
  • Access to an online chat forum with other carers
  • Completion of 4 sets of online questionnaires over a 12-month period

Carers will be randomly allocated to one of three conditions within the study, with all carers receiving access to the 8 modules and chat forum.

Adults with anorexia whose carers are participating in the programme will also have the opportunity to complete a set of 4 online questionnaires over a 12-month period. 

 

How long does it take?

The total duration of the study is 12 months, with participants completing the 8 online modules over a 12-week period.

 

Where will the study take place?

All parts of this study will be conducted online.

 

Inclusion Criteria

Carers

  • Aged 18+
  • Providing unpaid care for an adult (aged 16+) with a diagnosis of anorexia nervosa
  • Fluent in English

Participants with anorexia

  • Have a current diagnosis of anorexia nervosa, OR have been recently been diagnosed with anorexia nervosa, while currently meeting the criteria for another eating disorder (for example, individuals who have been recently weight-restored, but would meet all other criteria for anorexia nervosa).
  • Aged 16+
  • Fluent in English

 

Exclusion Criteria

Carers

  • Caring for a person with an eating disorder other than anorexia, who has never been diagnosed with anorexia
  • Carer currently suffering from an eating disorder
  • Unable to read and understand English

Participants with anorexia

  • Never having received a diagnosis of anorexia nervosa
  • Currently dependent on alcohol or drugs
  • Diagnosed with a current major psychological disorder, which would interfere with the participants’ ability to participate
  • Under the age of 16

 

Contact

For further information, please contact: lucy.spencer@kcl.ac.uk

 

Funding

The project is part of ICare, a European-wide research project funded by the European Commission, which aims to implement internet-based interventions that prevent mental health problems in different settings across Europe https://www.icare-online.eu/en/icare.html

EU Commission Logo

Effects of Intranasal Naloxone on Eating Behaviours in Bulimia Nervosa

We are looking for women with bulimia nervosa who would be interested in trying a new treatment. This study is looking to see if a nasal spray containing a well-known drug (naloxone hydrochloride) can help with the symptoms of bulimia nervosa.

What is the purpose of the research?

Naloxone hydrochloride nasal spray is being developed for treating eating behaviours in patients with bulimia nervosa. The aim of this study is to find out how well the nasal spray affects binging and eating behaviours in patients with bulimia nervosa.

Who can take part?

Female participants aged 18-60, fluent in English, who have a current diagnosis of bulimia nervosa and must:

  • Not have recent or current drugs or alcohol abuse
  • Not be taking opioid analgesics or other medication delivered to the nose
  • Not be pregnant or be likely to become pregnant

Eligibility will be fully assessed by the hospital team.

What does the study involve?

If you are interested in taking part, a member of the research team will be in touch by phone to discuss the study. If you meet basic eligibility criteria, you will then be invited to visit a clinic. During the study, you will need to attend the clinic on four occasions for between 2 and 5 hours, over a 12-week period.

On the first visit, it will be determined if it is appropriate for you to participate in the study. If you are happy to continue you will be asked to sign consent forms, one of which is for you to keep. Please note: participation in this study requires the answer to survey questions about your weight and measurements of your weight and height.

The study includes a 2-week screening period where you will be asked to complete some brief questions on your eating behaviours in an electronic diary every day. If you are suitable for the study you will receive either a nasal spray of naloxone or matching placebo.  A placebo is a ‘dummy treatment’, which looks like the genuine medicine but contains no active ingredient. You will have an equal chance of being allocated one of the two treatments which is decided by a computer. You should take your allocated treatment as instructed and complete the electronic diary every day for the 8-week treatment period.

During the visits, you will be asked to undergo physical examination, drug test, pregnancy test, blood test, smell test and complete a series of questionnaires. On two of the visits there will be a ‘taste test’ during which participants will rate the flavours of four different types of food.

After the treatment period, there will be a 2-week follow-up phase to ensure there are no safety issues after you have finished taking the product.

Participants will be reimbursed up to £130 (store vouchers) for their time.

How can you take part?

If you are interested in taking part, or would like more information without obligation to take part, you can contact the research team by email at: monica.leslie@kcl.ac.uk

 

A step by step guide for friends & family to become a Recovery Mentor

 

                              Information for carers  

You are invited to take part in a research project evaluating a new DVD which has been written, produced, and directed by carers, patients, & clinicians with experience of eating disorders to train family and friends to become a recovery mentor. 

Aim: We wish to assess whether the DVD, as an adjunct to treatment as usual, is effective for improving eating disorder symptoms. We also aim to test whether the SUCCEED DVD impacts distress in friends and family.

What’s involved: Individuals receiving treatment for an eating disorder, and their friends & family, who have a supportive role in recovery, can take part. 

We will ask you all to complete a series of questionnaires (now, in 2 month’s, and in 6 month’s time). Family & friends will be randomly allocated to start training to be a Recovery Mentor now or after a short waiting period. 

If you think you might be interested, please visit:

 

Contact: 

Email: charlotte.c.rhind@kcl.ac.uk  Tel: +44 (0) 20 7848 5963 

FABCAT: Food-Attention Bias Computerized Attention Training for Anorexia Nervosa

This project is an investigation into the therapeutic effects of a computerized attention training for patients with Anorexia Nervosa (AN). Such attention training, derived from clinical psychology research, has had promising effects on symptom reduction in other disorders such as depression and anxiety.

 

Aims:

The primary aim is to determine if a computerized attention training improves treatment outcomes, such as eating disorder symptoms and related difficulties, such as anxiety. Our secondary aim is to explore underlying mechanisms that contribute to these improvements. This will help us to determine if such a training could become part of usual clinical care for people with eating disorders.

 

What’s involved?

During a first assessment (baseline) participants will undergo a 1h-MRI scan, some questionnaires and some computer tasks. This session will last for about 3h (including MRI scan). 
Participants will then be assigned to either the experimental condition or a control condition of our attention training module which consists of three sessions usually within two weeks (approximately 30 minutes each).  
After the last training session, all participants will complete a post-assessment session involving the same measures as the pre-assessment (including another 1h-MRI scan). Four weeks after this assessment, participants will be contacted for a brief follow-up questionnaire and an online survey. Both follow-up measures can be completed online (e.g. at home).

 

Inclusion criteria:

You are eligible to take part if you:

  • are female and aged 18 or older
  • have a BMI less than 18.5
  • have a current diagnosis of AN-restricting type, AN-binge/purging type or EDNOS-anorexia type.

 

Exclusion criteria:

You are not eligible to take part if you are, or ever have been:

  • on a dose of any psychoactive medication that has not been stable for at least 14 days prior to participation in the study
  • experiencing another major psychiatric disorder (eg major depressive disorder, substance dependence, schizophrenia or bipolar disorder) needing treatment in its own right
  • experiencing learning and developmental impairments.

 

Compensation:
You will be compensated with £75 for your time and efforts of participating upon successful completion of all parts of this study and the follow-up assessment.

Contact: 

Email: daniela.mercado_beivide@kcl.ac.uk

Phone: 0207 848 5608

CytAN: Cytokines in individuals with a diagnosis of anorexia nervosa

This project aims to understand the role of the immune system, specifically cytokines, in anorexia nervosa. Our brain and behaviour are influenced by the immune system. Cytokines are important messenger molecules in the immune system. There are many different types of cytokines with different roles. They can be measured in the blood and can tell us a lot about inflammation in the body. Research has shown that individuals with a diagnosis of anorexia nervosa tend to have elevated levels of certain cytokines in their blood. However, very few cytokines have been measured and there are a number of cytokines that are important for the immune system and the brain that have never been measured in individuals with a diagnosis of anorexia nervosa. Also, we do not know whether cytokine levels are different in individuals with a diagnosis of anorexia nervosa who have different clinical characteristics. These include factors such as illness duration, eating disorder symptom severity, and severity of co-existing disorders (e.g. depression).

 

Aims:

In this study, we want to measure a large range of cytokines to find out if the level of cytokines differs between healthy control participants and individuals with a diagnosis of anorexia nervosa. We also want to investigate whether cytokine levels are related to certain clinical characteristics. This study will help us to understand if cytokines are involved in the underlying biology of anorexia nervosa. As there are medications available to influence cytokine production, cytokine levels and cytokine effects, our research may lead to the development of future treatments to help with anorexia nervosa.

 

What’s involved?

Once you have read and understood the information sheet you will have a brief phone call with a researcher to check your eligibility. If you are eligible you will arrange a 1-hour research session at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London (London, SE5 8AF). In this session, you will complete a short questionnaire pack, have your height, weight and body composition measured, and you will provide blood samples. All data will be kept anonymous.

 

Who can take part?

Inclusion criteria - You are eligible to take part if you:

  • Are a female aged 18 or older
  • Have a current diagnosis of Anorexia Nervosa
  • Have a body mass index (BMI) less than 18.5kg/m2.
  • Are fluent in English

 

Exclusion criteria - You are not eligible to take part if you:

  • Have current acute or chronic inflammatory conditions (e.g. asthma, Crohn’s disease, arthritis, psoriasis, inflammatory bowel disease)
  • Are pregnant

 

Compensation:

You will be reimbursed £5 for your time and efforts.

 

How can you take part?

If you are interested in taking part, or would like more information, you can contact Olivia or Bethan at:

Email: olivia.patsalos@kcl.ac.uk               Phone: 0207 848 5977

Email: bethan.l.dalton@kcl.ac.uk             Phone: 0207 848 0183

 

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