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Research

SGDP Statistical Genetics

The Statistical Genetics Unit (SGU) is a cross-school unit, comprising researchers at the Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, and the Department of Medical and Molecular Genetics, Faculty of Life Sciences and Medicine. SGU aims are to develop and support methods in statistical genetics, with a particular focus on common, complex disorders. The SGU comprises 25 researchers with diverse academic backgrounds including mathematics, statistics, molecular biology, clinical medicine and psychology, and we warmly welcome new members.

 

At the SGDP, our research programmes include:

  • Genome-wide association studies in psychiatric disorders, particularly major depressive disorder
  • Behavioural genetics modelling in twin and family data
  • Risk prediction using polygenic risk scores
  • Dissection of genetic correlations between psychiatric disorders, physical disorders
  • Pharmacogenetics and the genetic prediction of response to treatment.

 

Our research and researchers are funded by the NIHR Maudsley Biomedical Research Centre, MRC, Wellcome Trust, BBSRC and the NIH. Much of our research is carried out in close collaboration with the Psychiatric Genomics Consortium.

The Statistical Genetics Unit is headed by Professor Cathryn Lewis who obtained her PhD in Statistical Genetics at the University of Sheffield, and then worked at the University of Utah, Salt Lake City, before joining King’s College London in 1996, and the Institute of Psychiatry, Psychology and Neuroscience in 2007. 

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