Wolfson CARD receives two MRC grants to combat demyelination and fibromyalgia
Posted on 17/10/2018
We are delighted to announce that two scientists from the Wolfson have been awarded highly competitive MRC grants!
Dr Nicola Hamilton-Whitaker has been awarded an MRC New Investigator Research Grant of £ 519,140 (FEC) for a project entitled “TRP channels and white matter function in health and disease”. To allow nerve cells to transmit information rapidly over long distances, oligodendrocytes wrap myelin sheaths around their axons. Myelin damage, which is prevalent in many neurological diseases, is a major social and economic cost to society. But we still do not fully understand the processes that lead to myelin damage. Nicola will study the mechanisms that control myelination and cause myelin damage using transgenic mice and animal models of demyelinating diseases. This will allow her to define important biological processes involved in demyelination and will provide us with novel opportunities to discover targets for developing treatments to prevent myelin damage.
David Andersson, has been awarded an MRC Research Grant of £705,433 (FEC) to identify the pathophysiological basis of pain in Fibromyalgia. Patients with fibromyalgia experience widespread pain, sleep disturbances and memory problems, but the currently available therapies are not effective in most patients. Although fibromyalgia affects more than 2% of the general population, the mechanisms responsible for the syndrome are unknown and there are no established experimental models of the syndrome.