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Malcangio Lab

Malcangio Lab publications

macrophages and NeuN in DRG 1 large
  • Nieto-Lopez F, Clark A, Grist J, Chapman V, Malcangio M Calcitonin gene-related peptide expressing sensory neurons and spinal microglial reactivity contribute to pain states in collagen-induced arthritis. Arthritis Rheumatol. 67:1668-77, 2015
  • Old EA, Nadkarni S, Grist J, Gentry C, Bevan S, Kim KW, Mogg AJ, Perretti M, Malcangio M. Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain. J Clin Invest. 124:023-2036, 2014
  • Clark AK, Malcangio M. Microglial signalling mechanisms: Cathepsin S and Fractalkine. Exp Neurol.234:283-92,  2012
  • Clark AK, Wodarski R, Guida F, Sasso O, Malcangio M. Cathepsin S release from primary cultured microglia is regulated by the P2X7 receptor. Glia, 58: 1710-1726, 2010
  • Clark AK, Staniland AA, Marchand F, Kaan TK, McMahon SB, Malcangio M. P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide. J. Neurosci, 30: 573-582, 2010.
  • Clark AK, Yip PK, Malcangio M. The liberation of fractalkine in the dorsal horn requires microglial cathepsin S. J. Neurosci. 29: 6945-6954, 2009
  • Clark, A.K., Yip, P., Grist, J., Gentry, C., Staniland, A.A., Marchand, F., Dehvari, M., Wotherspoon, G., Winter, J., Ullah, J., Bevan, S.B., Malcangio, M. Inhibition of spinal microglial cathespin S for the reversal of neuropathic pain. Proc. Natl. Acad. Sci. USA, 2007,104 (25) 10655-10660
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