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ROS and Mitochondria in Nervous System Function and Disease

Location
Charles Darwin House 12 Roger Street London WC1N 2JU
Category
Conference/Seminar
When
27 (09:00) - 29/03/2017 (18:00)
Registration URL
https://www.biochemistry.org/Events/tabid/379/View/Conference/MeetingNo/SA195/Default.aspx
Description

A Biochemical Society Focused Meeting

 

Reactive oxygen species (ROS) and mitochondria have key roles in neuronal function and neurological disease. Many outstanding questions remain about the basic mechanisms involving ROS and normal neuronal function and how they contribute to disease. This meeting will provide a cutting edge forum to address these issues by bringing together leading scientists, as well as researchers who are new to the field, to present their current research and discuss future directions.

 

ROS have long been known to be damaging by-products of metabolism, but the concept that ROS modification of proteins plays a signalling role in the general function of neurons is rapidly gaining ground. Mitochondria generate ATP, but are also important organelles in neuronal signal transduction and are the main source of ROS. This meeting will explore how the roles of ROS and mitochondria intersect in neuronal signal transduction, the underlying biochemical processes and how these mechanisms modulate neuronal function. ROS and mitochondrial signalling are vitally important, not only in nervous system development and function, but also in neurological disease. The meeting will be relevant to researchers interested in basic mechanisms, but also those studying clinical aspects relating to diseases such as Parkinson’s disease, Alzheimer's disease and Amyotropic Lateral Sclerosis among many others.

 

The major themes of the meeting are:

 

1.    ROS in signal transduction

2.    Mitochondria as a signalling organelle

3.    ROS and mitochondrial signalling in neuronal function

4.    New techniques for visualising ROS and mitochondria

5.     ROS and mitochondrial signalling in translational medicine

 

Programme coordinators  Joseph  M. Bateman (King's College London, United Kingdom)

Sean Sweeney (University of York, United Kingdom)

 

Please click here for more information and booking details.

www.biochemistry.org

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