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Muscle: Form and Function

Ellison-Hughes Group

Biography

I am Reader of Physiology and Marie Curie Fellow in the Centre of Human & Applied Physiological Sciences, King’s College London, UK. I am part of the Centre for Stem Cells & Regenerative Medicine at King’s College London and the BHF National Centre for Regenerative Medicine.

I have a BSc Sports Science (Physiology), First Class, and PhD entitled ‘Myocyte Death and Renewal in Skeletal and Cardiac Muscle’ supervised by Prof. David F. Goldspink, at Liverpool JM University. I carried out a post-doc (2003-2007), funded by the Americian Heart Association, in the lab of Dr. Bernardo Nadal-Ginard at New York Medical College and then Mount Sinai School of Medicine, NYC, USA. I integrated back into the EU through a Marie Curie International Re-integration grant in 2008. I was a Lecturer, Senior Lecturer, Reader at Liverpool JM University (2007-2012) before locating to King’s College London in 2013.

I am Associate Editor of Scientific Reports, Nature Publishing group and BMC Cell Biology. I am recipient of a Scholarship for academic excellence from the British Federation of Women Graduates (2003) and the Young Investigator of the Year (2005) at the European College of Sports Sciences (ECSS). I was recognised as one of Best of British Early Career Researchers at the House of Commons (2007). 

Research Interests

My research focuses on understanding the role of tissue-specific stem cells in the homeostasis and regeneration of striated (skeletal and cardiac) muscle, for repair and maintenance of muscle tissue, particularly preventing and treating a loss of muscle mass (i.e. with ageing and/or disease). My research has been at the forefront of pioneering research on adult-derived cardiac stem cells since its inception 15 years ago and has made a seminal contribution in the paradigm shifting work to establish the adult heart as a self-renewing organ with regenerative capacity. I have extensive expertise in cardiac stem cell biology and regeneration, including the development of novel animal models of muscle damage-regeneration.

Publications and Funding 

A full list of publications can be found here.

Click here for funding information.

Group Members

Dr Fiona Lewis (Post Doctoral Researcher)

Dr PJ Ruchaya (Post Doctoral Researcher)

Dr Vicki Shone (Post Doctoral Researcher)

Tom Francis (PhD student - 2nd supervisor)

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