Jonathan Barker’s main research interests concern inflammatory skin diseases, such as atopic dermatitis and acne vulgaris, but primarily relate to psoriasis. In this disease, his interests extend from genetic discovery, through pharmacogenetics and disease mechanisms, such as immunology, to clinical research. To these ends, close collaborations exist with Richard Trembath (Genetics) and Frank Nestle (Immunology). Clinical research is conducted through the Skin Therapy Research Unit, which he co-directs with Dr Catherine Smith (Honorary Senior Lecturer). To date, over 170 peer-reviewed articles have appeared, many in high impact journals, most relating to this multifaceted approach to psoriasis research. In essence, Professor Barker’s research is aimed at delivering improved diagnosis, treatment and prevention of psoriasis via an integrated translational approach.