Comorbidities in Severe Psoriasis (CORE) study
About the study
The Comorbidities in Severe Psoriasis study (known as CORE) is a research project looking at the influence of other medical conditions (comorbidities) on the outcomes of treatment in patients with psoriasis. Recruited is now closed, 400 patients were recruited to the study.
Comorbidities are other significant medical problems that may occur in people with psoriasis, such as heart disease, cardio-vascular disease, obesity, and liver disease.
The study involved collecting information about a person’s psoriasis, such as their medical history, what treatments they have tried, and how long they have had the condition. This information could provide useful information on how a person reacts to their treatment. Blood samples were collected along with fibroscan and ultrasound scans of the liver.
The information obtained from analysis of these samples will help us understand better the disease processes involved in psoriasis and possibly lead to the development of new therapies.
Outcomes of the Research
The primary outcome of the study is to identify which factors are involved in whether or not treatment is successful or not. The secondary outcome is to understand more fully the role of comorbidities in severe psoriasis.