Key Publications
Cleaton MAM, Dent, CL, Howard M, Corish JA, Gutteridge I, Sovio, U, Gacciolo, F, Takahashi N, Bauer SR, Charnock-Jones, DS, Powell TL, Smith, GCS, Ferguson-Smith AC, Charalambous M. Fetus-derived DLK1 is required for maternal metabolic adaptations to pregnancy and is associated with fetal growth restriction. Nature Genetics October 2016.
Charalambous M, Da Rocha ST, Radford EJ, Medina-Gomez G, Curran S, Pinnock SB, Ferrón SR, Vidal-Puig A, Ferguson-Smith AC. (2014). DLK1/PREF1 regulates nutrient metabolism and protects from steatosis. Proc Natl Acad Sci U S A. Epub Oct 27.
Charalambous M, da Rocha ST, Hernandez A, Ferguson-Smith AC. (2014). Perturbations to the IGF1 growth pathway and adult energy homeostasis following disruption of mouse chromosome 12 imprinting. Acta Physiol (Oxf); 210(1):174-87.
Charalambous, M., Ferrón S. R., da Rocha, S. T., Murray, A. J., Hernandez, A., Ferguson-Smith, A. C*. (2012). Imprinted gene dosage is critical for the transition to independent life. Cell Metab 15(2): 209-212.
Charalambous, M., Cowley, M., Googehan, F., Smith, F. M., Radford, E., Hurst, L. D. H., Ward, A. Maternally-inherited Grb10 reduces placental size and efficiency (2010). Dev Biol 337:1-8.
Charalambous, M., Menheniott, T. R., Bennett, W. R., Kelly, S. M., Dell, G., Dandolo, L. and Ward, A. (2004). An enhancer element at the Igf2/H19 locus drives gene expression in both imprinted and non-imprinted tissues. Dev Biol 271, 488-97.
Charalambous, M., Smith, F. M., Bennett, W. R., Crew, T. E., Mackenzie, F. and Ward, A. (2003). Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism. Proc Natl Acad Sci U S A 100, 8292-7.