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Stroke

Stroke

The Stroke Research Team is a multidisciplinary team drawing on expertise from a range of research and health related disciplines including epidemiologists, stroke physicians, GPs, social scientists, statisticians and health economists.

Central to our internationally recognised stroke programme is the South London Stroke Register (SLSR). The SLSR is a population-based register set up in January 1995, recording all first-ever strokes in patients of all ages living in Lambeth and Southwark, inner city South London. At the 2011 census, the denominator population was 357,308 with 56% white, 25% black and 18% other ethnic groups. Our research interests include: epidemiology of stroke, natural history, stroke outcomes, access to services, stroke prevention, aetiology and classification of stroke, patients' experiences, development and testing of new services, methodological development and global health in stroke.

Aims

  • To establish the aetiology and epidemiology of the subtypes of stroke in different ethnic groups.
  • To understand the relationship between impairment, activity, participation and to develop appropriate methods to measure them.
  • To develop and conduct randomised controlled trials in the fields of stroke prevention, acute management, rehabilitation of stroke and long-term care.
  • To understand patient and family experiences.
  • To investigate ways of implementing findings and influencing policy.
  • To promote the involvement of stroke survivors and family in the design and conduct of our research and implementation of research evidence. 

Current Research Programme

The South London Stroke Register (SLSR)

The South London Stroke Register (SLSR) is an ongoing population- based stroke register recording first stroke in patients of all age groups. Data are collected prospectively by the registry team, comprising a specialist stroke physician and three research associates. By using 12 referral sources cases of stroke are identified in a defined area corresponding to 22 wards of Lambeth, Southwark, and Lewisham Health Commission.

The total population (357,308) is 56% white, 25% black (14% Black African, 7% Black Caribbean, and 4% Black Other), 6% Asian and 12% other ethnic groups. Hospital surveillance of admissions for stroke includes two teaching hospitals within and three outside the study area. Community surveillance of stroke includes patients under the care of all general practitioners within and on the borders of the study area (n=147).

The notification sources are accident and emergency records; hospital wards; brain imaging requests; death certificates; coroner's records; general practitioners; hospital medical staff; community therapists; bereavement officers; hospital based stroke registries; general practice computer records; and "miscellaneous," including notification by patients or relatives of patients. Methods are used to ensure complete ascertainment of cases.

Over the past 15 years more than 260 papers have been published and a total of £136.06 million in funding has been received from numerous funding sources such as the National Institute of Health Research (NIHR), the Medical Research Council (MRC), the Stroke Association, the Royal College of Physicians (RCP), the European Commission FP7 and Guy's and St Thomas' Charity.

Current Projects and Programmes

The South London Stroke Register data are used for all projects carried out in the research team, they include:

People & Contact us

Senior Principal Investigators

Saff members

Staff linked to the research team

  • Dr Salma Ayis - Lecturer in Medical Statistics
  • Bola Coker - Senior Data Manager
  • Dr Abdel Doiuri - Senior Lecturer in Medical Statistics
  • Dr Wang Yanzhong - Senior Lecturer in Medical Statistics
  • Dr Alison Wright - Lecturer in Health Psychology
  • Professor Peter Heuschmann - Visiting Professor in Clinical Epidemiology and Biometry, Institute of Clinical Epidemiology and Biometry (ICE-B), Würzburg, Germany
  • Professor Naomi Fulop - Visiting Professor of Health Care Organisation and Management, University College London
  • Dr Ajay Bhalla - Stroke Physician, Guy's and St Thomas' NHS Foundation Trust
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