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Biomedical Engineering & Imaging Sciences

Research

Our Research Departments

The School of Biomedical Engineering and Imaging Science is split into 5 research departments and the PET Centre. More information about each of these is listed below. 

Biomed

The Department of Biomedical Engineering provides cutting-edge engineering research and teaching within theSchool of Biomedical Engineering and Imaging Sciences, enhancing the School’s existing international reputation.

Our aims

Our main objective is to perform high-quality multidisciplinary research internationally. There is a close and vital relationship in our work between problem solving in clinical and biomedical application areas and methodological research in biomedical engineering technologies and information processing.

Through our translation of technology, we will support a shift from using predefined clinical indices to determine treatment options to true personalisation of care that is based on quantifying an individual’s specific physiology.

Our work

The School of Biomedical Engineering & Imaging Sciences is working to combine critical mass of basic science and clinical research with an outward-looking translational approach. Our research activity focuses on accelerating this by integrating intelligent image and data acquisition with quantitative tools in both clinical and basic science contexts.

We are combining cardiovascular, oncology and pulmonary disease applications with new areas of research. The goal of this work is to help gain the full value from state-of-the-art imaging and measurement tools and the information they produce.

Our specialisms

Our specialist areas include:

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Cancerupdated

Our strategic vision is to improve the outcome of patients by using imaging to personalise management, thereby improving the effectiveness of treatments and reducing their side effects 

We cover the spectrum from preclinical development to multicentre clinical trials ensuring that there is a translational pathway to clinical practice for our imaging research which includes the following modalities: ultrasound (US), computed tomography (CT), magnetic resonance imaging (MRI), single photon emission computed tomography (SPECT)/CT, positron emission tomography (PET)/CT, and PET/MRI as well as interventional radiology. 

Our imaging research is focussed on the following themes:

  1. Biomarker development, methodology, treatment planning
  2. Disease phenotyping & response prediction / evaluation & prognosis
  3. Development & optimisation of hybrid imaging
  4. Image analysis, processing & optimisation, bioinformatics and radiomics
  5. Multicentre clinical trials including programmes for clinical pathway development and optimisation 

As a department and clinical academic group we have a highly collaborative approach with close working relationships with other departments within the School of Biomedical Engineering and Imaging Sciences, other Schools within King’s College London, and with other institutions nationally and internationally.

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cadio

The Department of Cardiovascular Imaging is the most clinical Department in the School of Biomedical Engineering and Imaging Sciences. Our main goals are:

  • Delivery of a state of the art clinical service
  • Translation of novel technical developments into clinical applications
  • Validation, optimization and development of novel imaging techniques.

Our main interest is oriented towards cardiovascular disease mainly in the areas of myocardial ischaemia (coronary artery disease, heart attack), heart failure, electrophysiology and device therapy, vascular disease, especially aortic disease and heart disease in children and grown-ups with congenital defects.

Our research spans from preclinical and phantom work to large multicenter trials with the goal to support or change current guidelines.

Our specialisms

Our specialist areas include:

Useful Links:

ChemBio

Research in the Department of Imaging Chemistry and Biology is focussed on:

  • Identification of novel molecular imaging targets in all biomedical areas (cancer, cardiovascular, musculoskeletal, neurological, immunological) and development and evaluation of new molecular imaging agents for these applications
  • Novel chemical approaches to facilitate the development of novel contrast agents with simpler methodology, higher quality and wider availability for patients.

The Departmental research teams cover basic organic, inorganic and nanoparticle chemistry, and biology at the biomolecular, cellular and whole organism (preclinical and clinical) level. Research groups work together in a highly integrated way with a strong team ethos and boundaries between the research groups are extremely blurred. In this way we make exceptionally efficient use of our physical infrastructure, laboratory space and varied academic expertise. The Department is outstandingly well equipped with chemistry, radiochemistry, chemical and biochemical analysis (ES-MS, high field NMR, HPLC etc.), tissue culture and preclinical imaging facilities (PET/CT, SPECT/CT, 9.4 T MRI), with strong links to the PET Centre (with cyclotron and hot cell facilities and providing radioisotopes such as F-18, C-11, Cu-64, Cu-61, N-13, Ga-68 etc.) and Nuclear Medicine (providing access to isotopes such as Tc-99m, Ga-68 etc.).

The Department interacts closely with other departments in the School to optimise imaging capability and translate new science into clinical application.

Our specialisms

Our specialist areas include:

Useful Links:

perinatal

The Department of Perinatal Imaging and Health is a new department within the School of Biomedical Engineering and Imaging Sciences at King's College London.

Our goal is to reduce the number of children who suffer brain damage in the perinatal period through: improved understanding of the biology of cerebral injury and developmental disorders; better brain imaging particularly in utero and in the neonatal period; and clinical trials of novel therapies neuroprotective therapies.

We have established a new dedicated MR imaging suite in the Neonatal Intensive Care unit at St Thomas' Hospital, and we run a strongly collaborative approach working with colleagues around the world, particularly within The Centre for the Developing Brain which acts as a focal point to develop contacts and opportunities for research with industry, academia and research funders.

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pet

With more than 20 years experience of PET and PET-CT scanning and now also PET-MR, the Centre provides PET services for referred patients at a local and national level and performs clinically related research. We scan over 6000 patients per year, and the enhancements of our newly refurbished centre let us be there for our patients at every step of the experience and make it as smooth and comfortable as possible.

Our PET Centre is a centre of excellence with an international reputation for delivering the best patient care, highest quality academic research, and training. We strive to make a difference for the patients we scan, and via the research we perform.

 

Our mission is to perform basic, translational and applied clinical PET research across all specialties including oncology, neurology/psychiatry, and cardiology. We welcome work with external collaborators, including industry. We aim to obtain the best possible quality and reliability for all studies we perform.

The Centre develops exciting PET methodology (e.g. PET-MR), and also performs cutting-edge research into innovative radiochemistry using our in-house cyclotron and our wide range of multidisciplinary expertise.


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