Dr Thomas Iskratsch
Tel: +44 (0) 20 7848 6498
Thomas is a principal investigator at the Randall Division, King’s College London interested in the mechanical regulation of cardiac muscle formation and disease. He was first introduced to muscle research during his master thesis on the glycosylation profiles of dystrophic vs. healthy skeletal muscle at the University of Natural Resources and Life Sciences in Vienna. He then moved to King's College London to take on his PhD studies in Elisabeth Ehler’s lab on actin assembly factors that are involved in cardiac actin filament polymerization and maintenance. After the PhD he stayed on for a short post-doc before he joined the lab of Prof Michael Sheetz at Columbia University, New York for postdoctoral studies on the role of actin assembly proteins in integrin adhesion formation and mechanosensing, where he received extensive training on the tools and methods of biophysics and mechanobiology. However, he kept a strong interest in cardiovascular biology and successfully applied for a postdoctoral fellowship from the American Heart Association to combine both mechano- and cardiovascular biology and study the regulation of actin assembly proteins downstream of mechanical signals in cardiomyocytes
In January 2015 Thomas was awarded a British Heart Foundation Intermediate Basic Science Research Fellowship to establish his own lab at the Randall Division where he studies the mechanical regulation of myofibril assembly during heart development and disease.
2015 – present
: Principal investigator at the Randall Division of Cell and Molecular Biophysics. Postdoctoral Research:
Postdoctoral Fellow (American Heart Association Postdoctoral Fellowship), Department of Biological Sciences, Columbia University, New York 2011-2013:
Postdoctoral Research Associate, Department of Biological Sciences, Columbia University, New York
2009-2011: Postdoctoral Research Associate, Randall Division of Cell and Molecular Biophysics and Cardiovascular Division, King’s College London
PhD in Cardiovascular Medicine, Randall Division of Cell and Molecular Biophysics and Cardiovascular Division, King’s College London; Awarded September 2009.