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Gould Group

Professor Hannah Gould


Group leader

Senior Research Fellow
Randall Division of Cell and Molecular Biophysics and Division of Allergy, Asthma and Lung Biology
Tel: 44 (0)20 7848 6442
Fax: 44 (0)20 7848 6435


  • BA, MA Biochemistry, Radcliffe College 1959/60
  • PhD Biochemistry, Harvard University 1963
  • Post Doc, National Institute for Medical Research London 1963-1966
  • Post Doc, University College London 1967
  • MRC Scientific Staff, Metabolic Reactions Research Unit Imperial College London 1967-1969
  • Lecturer in Biophysics, King's College London 1969-1980
  • Reader in Biophysics, King's College London 1980-1987
  • Professor of Biophysics 1987- present
  • Senior Research Fellow 2001 - present

Expertise and skills

Molecular biology and Immunology

Research interests

Structure, function and regulation of IgE and its receptors and the pathogenesis of allergic disease

Research projects

  • Local IgE regulation
  • Mechanisms and regulation of immunoglobulin heavy-chain swiching to IgE
  • Signal transduction by IgE receptors
  • Mechanisms of tolerance induction by allergen-specific IgG4 and IgA
  • Anti-IgE immunotherapy of allergy
  • IgE immunotherapy of cancer

NIHR collaborations: ongoing pre-clinical and clinical trails

  • Guy’s & St. Thomas’ Trust (with CJ Corrigan): Efficacy of anti-IgE (omalizumab) antibody in the treatment of non-atopic asthma
  • New Agents Committee, Cancer Research UK (with SN Karagiannis and J Spicer): Pre-clinical evaluation of the anti-folate receptor antibody, MOv18 IgE, in the treatment of ovarian cancer

Invited talks 2014-2017

  • Japanese Society for Immunology, December 2017
  • Symposium in honor of SLO Johansson, Stockholm, October 2017
  • German Society for Immunology, Hamburg, September 2016
  • Allergo Oncology Workshop, Utrecht, July 2016
  • FASEB, West Palm Beach, July 2016
  • American Academy Allergy Asthma & Immunology, Los Angeles, March, 2016
  • American Academy Allergy Asthma & Immunology, San Diego, March 2014
  • European Academy Allergy Asthma & Immunology, Copenhagen, June 2014


  • European Academy Allergy & Clinical Immunology (EAACI) Congress, June 2014: Paul Ehrlich Medal for “Improving Experimental Science”
  • American Academy of Allergy, Asthma & Immunology, Los Angeles, March 2016: 2016 Jerry Dolovich Memorial Lectureship

Selected publications 2014-2016

See link to Pure for all publications

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