Section Head: Dr Susan Cox
The Cell Imaging Section Biological Nanoimaging group aims to unravel the biological processes at work when molecules interact in living cells by developing and applying advanced optical imaging techniques. We use bioactive molecules in live/fixed cells, cellular organelles, tissues and whole organisms. With methods such as structured illumination (linear and non-linear) and 4Pi microscopy we aim to improve resolution, fluorescence lifetime imaging microscopy and single molecule imaging. The biomolecular specificity possible with optical methods has been particularly valuable in microscopy and live cell protein studies. Visualising these biological processes in the context of diseased states we hope to develop new ways of monitoring and manipulating them and help to predict drug target effects and their translation to organ and organism level physiology.
Research is funded by the MRC, BBSRC, EPSRC, The Wellcome Trust, The European Union Framework Programme, medical charities (Dimbleby Cancer Care, Cancer Research UK, Breakthrough Breast Cancer, British Heart Foundation) and industrial collaborations.
* Joint appointment with School of Cancer and Pharmaceutical Sciences
1 Joint appoitment with Department of Physics
2 Associate member based in the Department of Physics