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Gould Group

Research themes

  • Regulation of immunoglobulin heavy-chain class switching to IgE and B cell differentiation into plasma cells in vitro

  • Mechanism of rhinovirus exacerbation of asthma

  • Immunoglobulin repertoires in asthma and allergy vs. healthy subjects

  • Effect of allergen challenge on B cell trafficking in vivo

  • Unconventional modes of interaction between allergens and antibodies

  • Fundamental differences in the structure, function and regulation of different immunoglobulin classes

  • Germinal centre reactions in lymphoid and mucosal tissues in the bronchial mucosa 

  • Super-resolution imaging of membrane IgE activities in human B cells


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