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Gautel Group

Professor Mathias Gautel

BHF Professor of Molecular Cardiology

and Director

NGautelMathiasew Hunt's House
Guy's Hospital
London SE1 1UL

PA: Gabriele Wright





BHF Professor of Molecular Cardiology, GKT Medical School, Cardiovascular Division and The Randall Division of Cell and Molecular Biophysics.

Professor Gautel received his MD from Heidelberg University in 1991, and was then a post-doctoral fellow and visiting team leader (1996-1998) at EMBL Heidelberg, where he worked on his habilitation (MD PhD equivalent) in Biochemistry on titin-based sarcomere assembly at Heidelberg University in 1998. After nine years at EMBL, Professor Gautel was awarded a Heisenberg Fellowship by the German Research Foundation, and joined the Max-Planck-Institute of Molecular Physiology, Dortmund, as a group leader. He was appointed as Professor of Molecular Cardiology at King’s College London in 2002, and was awarded the British Heart Foundation Chair of Molecular Cardiology at King’s in 2008. He heads the Randall Muscle Signalling and Development Section, and the KCL BHF Centre of Research Excellence Muscle Cell Biology theme.

Professor Gautel was awarded the International Society for Heart Research (ISHR) Outstanding Investigator Award in 2009. He was elected as a Fellow of the Academy of Medical Sciences (FMedSci) in 2010.

The laboratory uses molecular genetic, cell biophysical and biophysical, biochemical, structural, and physiological methods to study the biological principles that underpin sarcomere assembly, signaling, and controlled proteolytic turnover. Current areas of interest include mechanosignalling by muscle cytoskeletal proteins, their cross-talk with the proteolytic systems of muscle and gene expression regulation, and the perturbation of these processes in acquired and inherited muscle diseases.

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