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Research groups

Diabetes Research Group at Guys



Senior Lecturer in Physiology


Research Interests

  • Obesity and Diabetes
  • The Gut-brain axis and energy homeostasis
  • Gut-islet cross talk
  • Enteroendocrine function and cell fate

Bewick, Dr Gavin


Senior Lecturer in Physiology


Research Interests

  • Gestational diabetes
  • The beta cell adaptation to pregnancy
  • Regulation of the functional beta-cell mass

Bowe, Dr James


Lecturer in Diabetes and Nutrition


Research Interests

  • Determining the molecular mechanisms which underlie development of insulin resistance and beta-cell failure in T2D
  • Dietary polyphenols and metabolic health 
  • The impact of adverse intrauterine environments (maternal low-protein and high-fat diets) on metabolic health in the offspring

Caton, Dr Paul


Clinical Reader in Endocrinology and Diabetes


Research Interests

  • Immune and inflammatory pathways in the pathophysiology of obesity and the metabolic syndrome

Howard, Dr Jane


Professor of Endocrine Biology


Research interests

  • Cell-cell interactions in the regulation of islet function
  • Regulation of the functional Beta cell mass 
  • Encapsulation strategies for cell therapy
  • Stem cells and islet function

Jones, Prof Peter

Aileen King 

Senior Lecturer in Pharmacology


Research Interests

  • Improving islet function and survival in islet transplantation
  • Encapsulation strategies for islet transplantation

King, Dr Aileen

Bo Liu 

Research Associate


Research Interests

  • My post-doctoral research will involve the use of a variety of approaches that include studying the molecular/cell biology of the pancreatic β-cell, in vivomodels of diabetes and obesity, and discovering new phytotherapies for treating Type 2 diabetes

Liu, Dr Bo

Afshan Malik 

Senior Lecturer in Biochemistry and Molecular Genetics

Postgraduate Coordinator


Research Interests

  • The molecular pathways by which glucose-induced- changes can contribute to diabetic complications, with a particular emphasis on the role of mitochondrial dysfunction in this process

Malik, Dr Afshan


Professor of Diabetes and Endocrinology


Research interests

  • Stimulus-response coupling in mouse and human islet b-cells
  • Role of G-protein-coupled receptors in islet function
  • Novel insulin secretagogues

Persaud, Prof Shanta 

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