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Diet & Gastrointestinal Health

About Diet & Gastrointestinal Health

The Diet & Gastrointestinal Health research group aims to understand the molecular and cellular mechanisms that lead to non-communicable disorders of the gastrointestinal tract. Areas of expertise include normal and altered digestion and disorders of the gut including inflammatory bowel disease, constipation and irritable bowel syndrome, and the extent to which these are influenced by diet.

A major focus is the role of the gastrointestinal microbiota in health and disease, and in particular their interaction with genetics and the immune system in inflammatory bowel disease. We specialise in investigating how this interaction can be modified, for example, using pharmacogenetics and dietary approaches. Examples of dietary approaches include probiotics and prebiotics and modification of fibre and fermentable carbohydrate consumption.

In addition, we use proteomic techniques to study the effects of trauma and alcohol on protein turnover and tissue repair, and the effects of oxidative stress on these processes and nutritional support and clinical nutrition.

Research in the Diet & Gastrointestinal Health research group is funded by the BBSRC, MRC, industry and various medical research charities.

The Diet & Gastrointestinal Health group is led by Professor Kevin Whelan.

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