Bethan's PhD project uses a combination of atomistic and molecular modelling techniques to investigate the working mechanisms of viscosity-sensitive fluorescence probes, fluorescent molecular rotors (FMRs). These molecules have a rotatable portion which twists upon photoexcitation. This twisting is dependent on the local environment so links viscosity to the fluorescence lifetime. Her goal is to better understand the photophysics of these dyes so that we can improve the experimental methods available with them.
Before arriving at King’s Bethan completed an MPhys in Physics with Professional Experience at the University of Exeter. This included a year in industry, working in the Numerical Modelling and Optimisation section at TWI. Although Bethan loved working on commercial projects, she especially enjoyed having her own role within a large research project, in which she had to develop thermodynamic finite element models of steel welding. It was the intellectual freedom and academic challenge of this experience that convinced her to do a PhD.
Whilst at Exeter Bethan was heavily involved in Academic Representation as the chief rep for my her college. She has continued thus interest in the student experience at King’s as the BPSM and Physics PhD representative. Bethan has also undertaken a three-month internship and some freelance work with the Higher Education Policy Institute (HEPI).
Unravelling the Working Mechanisms of Fluorescent Molecular Rotors for Bioimaging
- Computational Chemistry
- Mixed Quantum/Classical molecular (QMMM) simulations
PhD supervisor: Professor Carla Molteni