Health
Sepsis, pandemic sciences and host-response biology
Aims
Through an interdisciplinary approach that integrates translational human immunology, microbiology, epidemiology, and data science, our aims are to identify, develop, and test effective treatments to enhance patient-centric outcomes in critical illness syndromes, such as sepsis and acute respiratory distress syndrome. Our research themes are designed to refine infection/sepsis diagnostics, including the identification of biomarkers, the identification of treatable molecular mechanisms and drug targets, precision immunomodulation, and emerging pandemic threats.
Research themes
- Systems immunology of sepsis and other critical illness such as ARDS
- Response to immunomodulation and precision immunobiology
- Infection and host-response to infection diagnostics and biomarkers
- Pandemic preparedness, drug discovery and early phase studies
Leadership
- Prof Manu Shankar-Hari and Dr Jonathan Cohen
Theme Membership and Internal collaborators
- Dr Chad Swanson (KCL)
- Professor Mike Malim (KCL)
- Professor Graham Lord (KHP)
- Professor Jonathan Edgeworth (GSTT)
- Professor Akash Deep (KCL)
- Dr Andrew Retter (GSTT)
- Dr Alexander Kaputskin (Visiting Fellow)
- Dr Teddy Tun Win HLA (AI researcher)
- Dr Jasmin Islam (Infectious Disease)
- Dr Luke Blagdon Snell (NIHR Clinical Lecturer in infectious diseases)
- Dr Gaia Nebbia (GSTT)
Project status: Starting