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Cardiovascular Sciences




Our Cardiovascular Sciences Section is headed by Professor Ajay Shah and based in state-of-the-art laboratory facilities at the James Black Centre within the Denmark Hill campus, adjacent to King’s College Hospital. 

We study how the heart adapts to disease stresses or fails, with a focus on identifying new pathophysiological mechanisms and potential therapies. Major areas of research include mitochondrial dysfunction, cardioprotective signalling, inflammatory mechanisms and heart regeneration. 

We are a very multi-disciplinary group pursuing a broad range of laboratory and clinical research and teaching, with a strong focus also on research training and mentorship.

Professor Ajay Shah



Our research

Our main research interests are in:

- the pathophysiology of cardiac remodelling and heart failure

- autophagy and mitophagy in heart disease

- cardiac regeneration and novel biotherapies for heart disease

- redox signalling and NADPH oxidases in cardiovascular disease

- inflammatory mechanisms in heart disease

- nuclear laminopathies and inherited heart disease



Our research groups

£30M funded state-of-the-art laboratory facilities

Close partnership with King’s College Hospital

Provide an outstanding research training environment