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Muscle Biology


Our Muscle Biology Section is headed by Dr Elisabeth Ehler and based in New Hunt’s House at Guy’s campus.  

This section is closely connected with the Randall Centre for Cell & Molecular Biophysics and its members use mainly biophysical techniques to study striated muscle in health and disease.  

Our main focus is on heart muscle and our interests range from the molecular level, where we are looking at the structure of proteins that make up the muscle and their interactions with each other, to the cellular level, where we want to find out, how the structures that make a heart cell do its work are assembled during development and how they are altered in heart disease. In addition, we study signalling pathways that make a muscle cell respond to an increased work-load with the ultimate goal to identify drugs that can slow down or even prevent maladaptive changes. 

We are a bijou group of scientists who try to answer questions on heart disease using mainly biophysical methods

Dr Elisabeth Ehler



Close connection with the Randall Centre for Cell & Molecular Biophysics

Centre for Biomolecular Spectroscopy

Nikon Imaging Centre