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Microbiome in Health & Disease MSc

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Our Microbiome in Health & Disease MSc provides students with a unique background in all aspects of both analysis of microbiome and determining the role of microbiome in pathology with experience in both computational and experimental techniques.

Designed and delivered by the newly established Centre for Host-Microbiome Interactions (CHMI) at King’s, the course brings together teaching on a varied course incorporating systems biology and bioinformatics with molecular biology, microbiology, immunology and physiology.


Key benefits

  • Deep understanding of microbial communities and their impact on host health and disease.
  • Focus on translation in clinical, agricultural and environmental challenges.
  • Opportunity to undertake research in collaboration with industrial partners.

In the post-human genome project world, our health is dependent on more than our genes. High throughput sequencing reveals the amazing complexity and extent of the microbial communities that reside within or upon us. We are also beginning to understand just how dynamic the interactions between the host and members of communities are. Interactions are diverse, and variations observed between individuals depend on a multitude of microbial and host factors, including diet and inflammatory status. More importantly, it is becoming clear that different disease states are linked to significant changes in the make-up of these communities. Scientists who understand the computational analysis of the huge data sets for microbial communities, and who are also able to interpret findings in the context of human and microbial health, will be in demand across this emerging field in academia and in industry.

Key information

Application status Open

Duration 1 year

Study mode Full-time

Credit value UK 180/ECTS 90

Course intake 15 students

Course leaders

Dr David Moyes

Dr Saeed Shoaie

 

Further details

Course contact for further information

david.moyes@kcl.ac.uk

saeed.shoaie@kcl.ac.uk

Course contact form Postgraduate admissions

Awarding institution King's College London

Faculty Dental Institute

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Course detail

Description

The MSc Microbiome in Health & Disease will provide you with a deep understanding of microbial communities and their diversity, and the impact of these communities on host health and disease. You will be exposed to the concepts and techniques involved in profiling and analysing large omics data sets associated with characterising and investigating microbial communities.

You will learn to analyse omics data sets, such as genome, transcriptome, metabolome and metagenome data, and how to integrate these data to develop a holistic understanding of the interactions between host and microbial communities in both health and disease states.

You will also learn how these skills apply in industry and have the opportunity to undertake research in collaboration with industrial partners. You will study the intersection between microbiome and engineering and learn how to identify and develop innovative products in different microbiome fields, applying learning from computational, multiomics analysis and basic biology, through advanced synthetic biology tools, and integrative analysis and modelling, to design new engineered therapeutic microbial communities and optimize their effectiveness in clinical, agricultural and environmental challenges.

You will also undertake a 10,000 word supervised dissertation on a subject within the field of microbiome in health and disease.

Course purpose

The course aims to develop students' knowledge of the microbial communities that reside within or upon us, and how they impact our health and disease processes.

It is designed for students who wish to improve their background knowledge and skills prior to applying for a PhD studentship, and also for students who wish to enhance their knowledge and skill set for analysing and interpreting the large, multiple omics data sets that are involved in microbiome research.

 

Course format and assessment

The MSc Microbiome in Health & Disease consists of 4 taught modules (two covering microbiology, microbial diversity and host-microbiome interactions, and two covering computational analysis of microbiome, and systems and synthetic biology), followed by a lab-based research project.  The taught component will run from September until January, with the research component running from February until August.

Teaching comprises conventional lectures, tutorials and computational workshops, supported by example sessions, project work and independent learning via reading material and online courses. During the computational modules, you will be provided with data sets to analyse for written and oral projects.

After completing the taught component, you will undertake a lab-based research project for which you will provide a proposal and subsequent dissertation and presentation under the guidance of a supervisor.

Teaching

The typical hours you will spend as you progress through your studies are as follows:

Lectures, seminars & feedback: 214 hours

Self-study: 1586 hours

Contact time is based on 24 academic weeks and self-study time is based on 31 academic weeks.

Typically, one credit equates to 10 hours of work.

Assessment

You may typically expect assessment by a combination of coursework (76%) and examinations (24%).

The study time and assessment methods detailed above are typical and give you a good indication of what to expect. However, they may change if the course modules change.

 

 

Extra information

Dr David Moyes

Course director, Dr David Moyes’ research interests focus on Host-Microbiome interactions; Microbiome; Mycobiome; host innate immune responses; epithelial cells and immunity. Recent research outputs include a collaborative and pioneering study to discover a toxin in the fungus Candida albicans, which plays a crucial role during human mucosal infection.

Dr Saeed Shoaie

Deputy course director, Dr Saeed Shoaie, is Lecturer in Host-Microbiome Systems Biology and Systems Medicine. His research interests focus analysing and integration of (Meta)’omics data in different cohort studies and aim to identify biomarkers and novel treatment strategies for human diseases, generation of genome-scale metabolic models for host and microbiome and apply them in personalized diagnosis and treatment. He has experiences in working with biotech companies and he applies these to set up stable collaborations between academia and industrial biotech companies.

Structure

Year 1

 

 

Required Modules

Courses are divided into modules. You will normally take modules totalling 180 credits.

You are required to take the following modules:

• Microbiology & Microbial Diversity (30 credits)

• Microbiome Analysis (45 credits)

• Systems & Synthetic Biology (30 credits)

• The Human Microbiome & Dysbiosis (15 credits)

• Research Project (60 credits)

King’s College London reviews the modules offered on a regular basis to provide up-to-date, innovative and relevant programmes of study. Therefore, modules offered may change. We suggest you keep an eye on this website for updates.

Optional Modules
There are no optional modules.

Entry requirements & how to apply

Microbiome in Health and Disease Entry Requirements
Minimum UK requirements  2:1

Bachelor's degree with 2:1 honours in computer sciences, mathematics, biological sciences, biotechnology, engineering or chemistry, or similar.

Applicants with a bachelor's (first) degree in subjects above with 2:2 honours who have significant prior laboratory or computational experience will be considered.

International requirements   Visit our admissions webpages to view our International entry requirements.
English Language requirements Band D Visit our admissions webpages to view our English language entry requirements.

 

Application procedure

Applications must be made online using the King’s application portal apply.kcl.ac.uk and a non-refundable application fee of £55 applies. Your application will be reviewed by the admissions tutor and we aim to respond to applications within four weeks, although this may take longer during busy and holiday periods.

 

Personal statement and supporting information

Please submit a personal statement with your application, demonstrating a focused interest in the area, and explaining why you wish to apply for this course and why you feel it matches your interests, academic background, and your career plans. Please include transcript of subjects taken in the relevant degrees and copies of all certificates and relevant qualifications mentioned in your application.

Application closing date

We recommend that you submit your application as soon as possible.  Our first application deadline is the 30th March 2018.  Applications will remain open if places are available and programmes will be closed as soon as they are full.  For programmes with spaces remaining, no further applications will be accepted from non-EU (Overseas) nationals after 27th July 2018 or from UK/ EU nationals after 31st August 2018.

Help and support

If you don't have a suitable qualification for direct entry to a UK university, or if English isn't your first language, our academic preparation courses can help you get ready for study in the UK.

Preparation courses

Fees and funding

  • Full time UK fees: £11,500 (2018/19)
  • Full time overseas fees: £23,940 (2018/19)
  • Part time UK fees: N/A
  • Part time overseas fees: N/A

Please note: Current regulations allow some students to pay UK tuition fees on the basis of their EU citizenship or residency. Until these eligibility criteria are changed, the EU tuition fee will remain the same as the UK tuition fee. 

These tuition fees may be subject to additional increases in subsequent years of study, in line with King’s terms and conditions.

Deposit

When you receive an offer for this course you will be required to pay a non-refundable deposit to secure your place. The deposit will be credited towards your total fee payment.

The UK/EU deposit is £500.

The INTERNATIONAL deposit is £2,000. 

  • If you receive an offer on or before 31st March 2018, payment is due by 27th April 2018.
  • If you receive an offer between 1st April 2018 and 30th June 2018, payment is due within one month of receiving the offer.
  • If you receive an offer between 1st July 2018 and 31st July 2018, payment is due within two weeks of receiving the offer.
  • If you receive an offer on or after 1st August 2018, payment is due within one week of receiving the offer.

If you are a current King’s student in receipt of the King's Living Bursary you are not required to pay a deposit to secure your place on the programme. Please note, this will not change the total fees payable for your chosen programme.

Additional costs

In addition to your tuition fees, you can also expect to pay for:

• books if you choose to buy your own copies

 

• personal photocopies

  • library fees and fines

• printing course handouts

• society membership fees

• conference attendance, travel and accommodation (optional)

• stationery

• graduation costs

• travel costs around London and for placements.

Please visit our web pages on fees and funding for more information.

 

Financial help and support

Visit the fees and funding webpages to find out more about bursaries, scholarships, grants, tuition fees, living expenses, student loans and other financial help available at King's.


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Next steps

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Page last modified on 02 January 2018.